Home > 分離済み変異体 > tm4152

分離済み変異体

Allele Name		tm4152
Balance		Not Required
OutCross		Not Accepted
Sequence Name		ZC374.1
Gene Name		gnrr-3
Worm Base	Allele Name	tm4152
	Gene Name	gnrr-3
	Sequence	ZC374.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		16292/16293-ATATCACT-16505/16506 (213 bp deletion + 8 bp insertion)
Chromosome		X
Putative gene structure		join(15450..15580, 15980..16113, 16155..16257, 16307..16466, 16522..16665, 18244..18471)
Map position		1.73
Balancer
Map position of balancer
Sequence of primers		ExtRev:TTCCGTAACTTAGGCTCCTC,IntFwd:CCTAAGCCGCGCATATAATT,IntRev:GTAACTTAGGCTCCTCCACT,ExtFwd:CATACTCGACTATCCGTGAT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Chai CM, Park H, Sternberg PW. Brain-wide bidirectional neuropeptide modulation of individual neuron classes regulates a developmental decision. Curr Biol 2022 32(15) 3365-3373.e6  [ PubMed ID = 35679871 ] [ RRC reference ] Kishner M, Habaz L, Meshnik L, Meidan TD, Polonsky A, Ben-Zvi A. Gonadotropin-releasing hormone-like receptor 2 inversely regulates somatic proteostasis and reproduction in Caenorhabditis elegans. Front Cell Dev Biol 2022 10 951199  [ PubMed ID = 36105349 ] [ RRC reference ] Van der Auwera P, Frooninckx L, Buscemi K, Vance RT, Watteyne J, Mirabeau O, Temmerman L, De Haes W, Fancsalszky L, Gottschalk A, Raizen DM, Nelson MD, Schoofs L, Beets I. RPamide neuropeptides NLP-22 and NLP-2 act through GnRH-like receptors to promote sleep and wakefulness in C. elegans. Sci Rep 2020 10(1) 9929  [ PubMed ID = 32555288 ] [ RRC reference ] Lemieux GA, Keiser MJ, Sassano MF, Laggner C, Mayer F, Bainton RJ, Werb Z, Roth BL, Shoichet BK, Ashrafi K. In silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feeding. PLoS Biol 2013 11(11) e1001712  [ PubMed ID = 24260022 ] [ RRC reference ]