分離済み変異体

tm4076

Allele Nametm4076
BalanceNot Required
OutCrossNot Accepted
Sequence NameT25E12.4
Gene Namedkf-2
Worm BaseAllele Name tm4076
Gene Name dkf-2
Sequence T25E12.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) [F14D1] 32117/32118-A-[Y70C5D] 1164/1165 (1646 bp deletion + 1 bp insertion)
ChromosomeV
Putative gene structurejoin(23733..23771, 23859..24048, 24606..24669, 32855..33156, Z92967.1:3825..3830, Z92967.1:4762..4949, Z92967.1:5886..6024, Z92967.1:11974..12239, 92967.1:12909..13034, Z92967.1:13138..13224, Z92967.1:13371..13479, Z92967.1:14545..14649, Z92967.1:15178..15269, Z92967.1:15582..15788, Z92967.1:16410..16590, Z92967.1:32164..32307, AL021507.1:451..1200, AL021507.1:1259..1269, AL021572.1:106..180, AL021572.1:858..935, AL021572.1:997..1143)
Map position11.16
Balancer
Map position of balancer
Sequence of primersExtFwd:GATAGCTTCGACAGCGTCAA,IntFwd:GCTCGGCAGAGCAGCAGATT,ExtRev:CGGAGTCACATTGTGCTCTT,IntRev:TCGTAAGCCTGCCACCTCAC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Clites BL, Frohock B, Koury EJ, Andersen EC, Pierce JT.
Natural variation in protein kinase D modifies alcohol sensitivity in Caenorhabditis elegans.
bioRxiv 2024   
[ PubMed ID = 38895441 ] [ RRC reference ]

Tsai Y, Lin YC, Lee YH.
Octopamine-MAPK-SKN-1 signaling suppresses mating-induced oxidative stress in Caenorhabditis elegans gonads to protect fertility.
iScience 2023 26(3) 106162 
[ PubMed ID = 36876134 ] [ RRC reference ]

Laurent P, Ch'ng Q, Jospin M, Chen C, Lorenzo R, de Bono M.
Genetic dissection of neuropeptide cell biology at high and low activity in a defined sensory neuron.
Proc Natl Acad Sci U S A 2018 115(29) E6890-E6899 
[ PubMed ID = 29959203 ] [ RRC reference ]

Liachko NF, McMillan PJ, Strovas TJ, Loomis E, Greenup L, Murrell JR, Ghetti B, Raskind MA, Montine TJ, Bird TD, Leverenz JB, Kraemer BC.
The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43.
PLoS Genet 2014 10(12) e1004803 
[ PubMed ID = 25473830 ] [ RRC reference ]