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分離済み変異体

Allele Name		tm4074
Balance		Completed
OutCross		Not Accepted
Sequence Name		T11G6.1
Gene Name		hars-1
Worm Base	Allele Name	tm4074 (x1)
	Gene Name	hars-1
	Sequence	T11G6.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		23260/23261-23921/23922 (661 bp deletion)
Chromosome		IV
Putative gene structure		join(22749..22844, 23234..23785, 23834..24242, 24290..24738, 24788..24844)
Map position		4.72
Balancer		nT1 [qIs51]
Map position of balancer
Sequence of primers		IntFwd:GAACTATTACGAGTAGGCTG,ExtFwd:ACGCGTTTGCAATCCGCATA,IntRev:GAGTGTCACGAACGGCAGTG,ExtRev:CGATTGTTTAGAGGGCGGCA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Mazzetto M, Gonzalez LE, Sanchez N, Reinke V. Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis. Genome Res 2024 34(1) 57-69  [ PubMed ID = 38164610 ] [ RRC reference ] Chung KW, Kim JS, Lee KS. A Database of Caenorhabditis elegans Locomotion and Body Posture Phenotypes for the Peripheral Neuropathy Model. Mol Cells 2020 43(10) 880-888  [ PubMed ID = 33115980 ] [ RRC reference ] Alriyami MZ, Jones MR, Johnsen RC, Banerjee Y, Baillie DL. let-65 is cytoplasmic methionyl tRNA synthetase in C. elegans. Meta Gene 2014 2 819-30  [ PubMed ID = 25606464 ] [ RRC reference ] C. elegans Deletion Mutant Consortium. large-scale screening for targeted knockouts in the Caenorhabditis elegans genome. G3 (Bethesda) 2012 2(11) 1415-25  [ PubMed ID = 23173093 ] [ RRC reference ] Pierce SB, Chisholm KM, Lynch ED, Lee MK, Walsh T, Opitz JM, Li W, Klevit RE, King MC. Mutations in mitochondrial histidyl tRNA synthetase HARS2 cause ovarian dysgenesis and sensorineural hearing loss of Perrault syndrome. Proc Natl Acad Sci U S A 2011 108(16) 6543-8  [ PubMed ID = 21464306 ] [ RRC reference ]