分離済み変異体

tm3968

Allele Nametm3968
BalanceNot Required
OutCrossNot Accepted
Sequence NameC44E4.1
Gene NameC44E4.1
Worm BaseAllele Name tm3968
Gene Name C44E4.1
Sequence C44E4.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 7245/7246-TATATACA-7940/7941 (695 bp deletion + 8 bp insertion)
ChromosomeI
Putative gene structurecomplement(join(4658..4846, 4897..5203, 5661..6103, 6416..7406, 7669..8063, 8286..8420, 8462..9141, 9192..9667, 10227..10531, 11193..12389, 12919..13325, 14065..15635, 16257..17163, 17233..17362))
Map position-1.04
Balancer
Map position of balancer
Sequence of primersExtFwd:TTTCGCCATATCCTGGGTCT,IntFwd:GCTCGTGTCGATTTAGGGAC,ExtRev:AGTCGAGCGATCCTGGAATG,IntRev:GGCCATTGATGCGTGATATC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

McDiarmid TA, Belmadani M, Liang J, Meili F, Mathews EA, Mullen GP, Hendi A, Wong WR, Rand JB, Mizumoto K, Haas K, Pavlidis P, Rankin CH.
Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation.
Proc Natl Acad Sci U S A 2020 117(1) 656-667 
[ PubMed ID = 31754030 ] [ RRC reference ]

Rinschen MM, Bharill P, Wu X, Kohli P, Reinert MJ, Kretz O, Saez I, Schermer B, Höhne M, Bartram MP, Aravamudhan S, Brooks BR, Vilchez D, Huber TB, Müller RU, Krüger M, Benzing T.
The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes.
Hum Mol Genet 2016 25(7) 1328-44 
[ PubMed ID = 26792178 ] [ RRC reference ]