分離済み変異体

tm3951

Allele Name

tm3951

Balance

Completed

OutCross

Not Accepted

Sequence Name

F10E9.8

Gene Name

sas-4

Worm Base

Allele Name

tm3951 (x1)

Gene Name

sas-4

Sequence

F10E9.8

Phenotype

lethal or sterile

Mutation site

38543/38544-39148/39149 (575 bp deletion)

Chromosome

III

Putative gene structure

complement(join(35732..36020, 36774..36833, 36882..37069, 37116..37274, 37545..37988, 38165..38697, 38740..38959, 39076..39420, 39501..39596, 39645..39737))

Map position

-0.33

Balancer

hT2 [bli-4(e937) let-? qIs48]

Map position of balancer

Sequence of primers

ExtFwd:CTAAAGTCTGTAGAGTGCTC,IntFwd:CTTTAGCCGGTTTCCGTCTT,ExtRev:GCCTTCAGATGGCTTCCGAT,IntRev:TATCGGTGCCGACGGTGAAC

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69
[ PubMed ID = 38164610 ] [ RRC reference ]

Serwas D, Su TY, Roessler M, Wang S, Dammermann A.
Centrioles initiate cilia assembly but are dispensable for maturation and maintenance in C. elegans.
J Cell Biol 2017 216(6) 1659-1671
[ PubMed ID = 28411189 ] [ RRC reference ]

Cabral G, Sans SS, Cowan CR, Dammermann A.
Multiple mechanisms contribute to centriole separation in C. elegans.
Curr Biol 2013 23(14) 1380-7
[ PubMed ID = 23885867 ] [ RRC reference ]

Mikeladze-Dvali T, von Tobel L, Strnad P, Knott G, Leonhardt H, Schermelleh L, Gönczy P.
Analysis of centriole elimination during C. elegans oogenesis.
Development 2012 139(9) 1670-9
[ PubMed ID = 22492357 ] [ RRC reference ]

Kitagawa D, Flückiger I, Polanowska J, Keller D, Reboul J, Gönczy P.
PP2A phosphatase acts upon SAS-5 to ensure centriole formation in C. elegans embryos.
Dev Cell 2011 20(4) 550-62
[ PubMed ID = 21497765 ] [ RRC reference ]