分離済み変異体

tm3949

Allele Nametm3949
BalanceNot Required
OutCrossNot Accepted
Sequence NameY87G2A.3
Gene Nameatg-4.1
Worm BaseAllele Name tm3949
Gene Name atg-4.1
Sequence Y87G2A.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 47069/47070-47385/47386 (326 bp deletion)
ChromosomeI
Putative gene structurecomplement(join(46352..46470, 47187..47813, 48082..48173, 49521..49749, 50412..50553, 50606..50661, 51264..51335, 51387..51531))
Map position21.38
Balancer
Map position of balancer
Sequence of primersIntFwd:ATCAACTTCCATATCGGGAC,ExtFwd:CGGCGCCGATGTCATCGAAT,IntRev:TCCCTCTCCCCAGGCAATAT,ExtRev:CCTCGTCGACAAAAACCGTC
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Chen HD, Kao CY, Liu BY, Huang SW, Kuo CJ, Ruan JW, Lin YH, Huang CR, Chen YH, Wang HD, Aroian RV, Chen CS.
HLH-30/TFEB-mediated autophagy functions in a cell-autonomous manner for epithelium intrinsic cellular defense against bacterial pore-forming toxin in C. elegans.
Autophagy 2017 13(2) 371-385 
[ PubMed ID = 27875098 ] [ RRC reference ]

Palmisano NJ, Meléndez A.
Detection of Autophagy in Caenorhabditis elegans.
Cold Spring Harb Protoc 2016 2016(2) pdb.top070466 
[ PubMed ID = 26832690 ] [ RRC reference ]