分離済み変異体

tm3947

Allele Nametm3947
BalanceCompleted
OutCrossNot Accepted
Sequence NameY87G2A.5
Gene Nameglp-4
Worm BaseAllele Name tm3947 (x1)
Gene Name glp-4
Sequence Y87G2A.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 65187/65188-AAAT-65689/65690 (502 bp deletion + 4 bp insertion)
ChromosomeI
Putative gene structurecomplement(join(57689..57757, 58958..59289, 61039..61338, 63130..63700, 64952..66024, 67110..67697, 68342..68561))
Map position21.44
BalancertmC27[tmIs1239]
Map position of balancer
Sequence of primersIntRev:CAGCGTCTAATTAGTGCTAG,IntFwd:GTCCAGTCTCCAACACAGCA,ExtRev:GGCTATGCGACTAAACCAAA,ExtFwd:CAGTCAACTCCTGAGCCATA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Rastogi S, Borgo B, Pazdernik N, Fox P, Mardis ER, Kohara Y, Havranek J, Schedl T.
Caenorhabditis elegans glp-4 Encodes a Valyl Aminoacyl tRNA Synthetase.
G3 (Bethesda) 2015 5(12) 2719-28 
[ PubMed ID = 26464357 ] [ RRC reference ]

Alriyami MZ, Jones MR, Johnsen RC, Banerjee Y, Baillie DL.
let-65 is cytoplasmic methionyl tRNA synthetase in C. elegans.
Meta Gene 2014 2 819-30 
[ PubMed ID = 25606464 ] [ RRC reference ]

C. elegans Deletion Mutant Consortium.
large-scale screening for targeted knockouts in the Caenorhabditis elegans genome.
G3 (Bethesda) 2012 2(11) 1415-25 
[ PubMed ID = 23173093 ] [ RRC reference ]