Home > 分離済み変異体 > tm394

分離済み変異体

Allele Name		tm394
Balance		Not Required
OutCross		Not Accepted
Sequence Name		C56A3.7
Gene Name		cav-2
Worm Base	Allele Name	tm394
	Gene Name	cav-2
	Sequence	C56A3.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. A. Antebi: normal gonadal migration. Dr. H. Baylis: defective lipid uptake in inetstine, alteration in endocytosis, slightly reduced brood size, Mol Biol Cell, in press. Dr. A. van der Bliek: Hermaphrodites are fertile. Normal locomotion. WT mitochondria in muscle. Dr. M. Labouesse: normal cuticle, molting, resistance to D. coniospora.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		31168/31169-A-32007/32008 (839 bp deletion + 1 bp addition)
Chromosome		V
Putative gene structure		join(30827..30898, 30946..31056, 31096..31194, 31242..31334, 31384..31473, 32138..32208, 32404..32539, 32991..33068, 33111..33233, 33286..33468)
Map position		5.45
Balancer
Map position of balancer
Sequence of primers		ExtFwd:CTGAAACTGGGTAAGCAAGA,IntFwd:TTGGCACGTCCTAGGCCAAA,IntRev:CCATAAACTTTGTCTCGTGG,ExtRev:AGGCAAAGGTGAAAGCCGGT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Parker S, Walker DS, Ly S, Baylis HA. Caveolin-2 is required for apical lipid trafficking and suppresses basolateral recycling defects in the intestine of Caenorhabditis elegans. Mol Biol Cell 2009 20(6) 1763-71  [ PubMed ID = 19158391 ] [ RRC reference ] Bae YK, Qin H, Knobel KM, Hu J, Rosenbaum JL, Barr MM. General and cell-type specific mechanisms target TRPP2/PKD-2 to cilia. Development 2006 133(19) 3859-70  [ PubMed ID = 16943275 ] [ RRC reference ]