分離済み変異体

tm3933

Allele Nametm3933
BalanceNot Required
OutCrossNot Accepted
Sequence NameC49C3.10
Gene NameC49C3.10a
Worm BaseAllele Name tm3933
Gene Name C49C3.10a
Sequence C49C3.10
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 26882/26883-27282/27283 (400 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(25970..26128, 26238..26433, 26475..26658, 26973..27141, 27270..27311, 27361..27468, 27514..27673, 27729..27803, 27902..28005))
Map position16.49
Balancer
Map position of balancer
Sequence of primersIntRev:GCGCGTATTGATTTTAGCTC,IntFwd:AGCGGCAATAGGGGACTTTC,ExtRev:TGAGACGGCAGAGAGTTATA,ExtFwd:ACATCCCAAGGACCAGATGT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Nix P, Hammarlund M, Hauth L, Lachnit M, Jorgensen EM, Bastiani M.
Axon regeneration genes identified by RNAi screening in C. elegans.
J Neurosci 2014 34(2) 629-45 
[ PubMed ID = 24403161 ] [ RRC reference ]

Liachko NF, McMillan PJ, Guthrie CR, Bird TD, Leverenz JB, Kraemer BC.
CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.
Ann Neurol 2013 74(1) 39-52 
[ PubMed ID = 23424178 ] [ RRC reference ]