分離済み変異体

tm390

Allele Nametm390
BalanceNot Required
OutCrossNot Accepted
Sequence NameW06A7.3
Gene Nameret-1
Worm BaseAllele Name tm390
Gene Name ret-1
Sequence W06A7.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable Dr. T. Toyoda: Biochem. Biophys. Res. Comm. 293, 697-704 (2002).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 12798/12799-13053/13054 (255 bp deletion)
ChromosomeV
Putative gene structureW06A7.3a.1= complement(join(12347..12413, 12490..12861, 12918..13068, 13512..13590)), W06A7.3a.2= complement(join(11928..12413, 12490..12861, 12918..13068, 14170..14372, 16386..16466, 16510..17323, 19088..19168, 20833..21123, 21182..21302))
Map position6.95
Balancer
Map position of balancer
Sequence of primersExtFwd:AGGGTCGCCGCAATCTACTT,IntFwd:TTCTCCTCGGTACTGCATAC,IntRev:GGACCAGGTCGTATAAGATA,ExtRev:GCGGAAGCAGTTAATGTGTT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Serot C, Scarcelli V, Pouget A, Largeau C, Sagot A, El-Hachami K, Dupuy D, Culetto E, Lefebvre C, Legouis R.
Reticulon-dependent ER-phagy mediates adaptation to heat stress in C. elegans.
Curr Biol 2025 35(10) 2365-2378.e7 
[ PubMed ID = 40328253 ] [ RRC reference ]

Sun J, Harion R, Naito T, Saheki Y.
INPP5K and Atlastin-1 maintain the nonuniform distribution of ER-plasma membrane contacts in neurons.
Life Sci Alliance 2021 4(11)  
[ PubMed ID = 34556534 ] [ RRC reference ]

Liu X, Guo X, Niu L, Li X, Sun F, Hu J, Wang X, Shen K.
Atlastin-1 regulates morphology and function of endoplasmic reticulum in dendrites.
Nat Commun 2019 10(1) 568 
[ PubMed ID = 30718476 ] [ RRC reference ]

Torpe N, Nørgaard S, Høye AM, Pocock R.
Developmental Wiring of Specific Neurons Is Regulated by RET-1/Nogo-A in Caenorhabditis elegans.
Genetics 2017 205(1) 295-302 
[ PubMed ID = 27821431 ] [ RRC reference ]