分離済み変異体

tm3827

Allele Nametm3827
BalanceNot Required
OutCrossNot Accepted
Sequence NameT11F1.8
Gene NameT11F1.8
Worm BaseAllele Name tm3827
Gene Name T11F1.8
Sequence T11F1.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 12333/12334-12507/12508 (174 bp deletion)
ChromosomeII
Putative gene structurecomplement(join(12031..12160, 12351..12418, 12468..12857, 13579..13854, 13900..14094, 14152..14409, 15013..15103))
Map position-9.2
Balancer
Map position of balancer
Sequence of primersExtFwd:TGACGGAGTAAGTAGGTGGT,ExtRev:TGTCGGCAGGTGCACAGGAT,IntFwd:GTAGGTGGTAATTACGCCGA,IntRev:ACTCAAACAGCCGACATCGT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Yu S, Driscoll M.
EGF signaling comes of age: promotion of healthy aging in C. elegans.
Exp Gerontol 2011 46(2-3) 129-34 
[ PubMed ID = 21074601 ] [ RRC reference ]

Iwasa H, Yu S, Xue J, Driscoll M.
Novel EGF pathway regulators modulate C. elegans healthspan and lifespan via EGF receptor, PLC-gamma, and IP3R activation.
Aging Cell 2010 9(4) 490-505 
[ PubMed ID = 20497132 ] [ RRC reference ]