分離済み変異体

tm3813

Allele Nametm3813
BalanceNot Required
OutCrossNot Accepted
Sequence NameK07B1.1
Gene Nametry-5
Worm BaseAllele Name tm3813
Gene Name try-5
Sequence K07B1.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 19584/19585-19895/19896 (311 bp deletion)
ChromosomeV
Putative gene structurejoin(19723..20163, 20205..20484, 20914..21011, 21055..21237)
Map position2.01
Balancer
Map position of balancer
Sequence of primersIntRev:CTTAGACCTACCCAAAGTCA,ExtFwd:AACACCTTATCTCCTGTCGT,IntFwd:CCTGTCGTTTCGATACATCT,ExtRev:TGCGTTGTAGAACTTAGACC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Liu P, Shi J, Sheng D, Lu W, Guo J, Gao L, Wang X, Wu S, Feng Y, Dong D, Huang X, Tang H.
Mitopherogenesis, a form of mitochondria-specific ectocytosis, regulates sperm mitochondrial quantity and fertility.
Nat Cell Biol 2023 25(11) 1625-1636 
[ PubMed ID = 37945830 ] [ RRC reference ]

Chavez DR, Snow AK, Smith JR, Stanfield GM.
Soma-germ line interactions and a role for muscle in the regulation of C. elegans sperm motility.
Development 2018 145(24)  
[ PubMed ID = 30470702 ] [ RRC reference ]

Fenker KE, Hansen AA, Chong CA, Jud MC, Duffy BA, Norton JP, Hansen JM, Stanfield GM.
SLC6 family transporter SNF-10 is required for protease-mediated activation of sperm motility in C. elegans.
Dev Biol 2014 393(1) 171-82 
[ PubMed ID = 24929237 ] [ RRC reference ]

Erkut C, Vasilj A, Boland S, Habermann B, Shevchenko A, Kurzchalia TV.
Molecular strategies of the Caenorhabditis elegans dauer larva to survive extreme desiccation.
PLoS One 2013 8(12) e82473 
[ PubMed ID = 24324795 ] [ RRC reference ]

Smith JR, Stanfield GM.
TRY-5 is a sperm-activating protease in Caenorhabditis elegans seminal fluid.
PLoS Genet 2011 7(11) e1002375 
[ PubMed ID = 22125495 ] [ RRC reference ]