分離済み変異体

tm3768

Allele Nametm3768
BalanceNot Required
OutCrossNot Accepted
Sequence NameF40F12.5
Gene Namecyld-1
Worm BaseAllele Name tm3768
Gene Name cyld-1
Sequence F40F12.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 9742/9743-10238/10239 (496 bp deletion)
ChromosomeIII
Putative gene structurecomplement(join(8582..8731, 8843..9554, 9627..9875, 10568..10884, 11173..11308, 11359..11507, 12150..12309, 12354..12456, 13402..13486, 16531..16635, 18671..18779, 18823..18899, 19180..19305, 19699..19938, 19993..20150, 20203..20239))
Map position1.15
Balancer
Map position of balancer
Sequence of primersExtFwd:GATCAGCCATCGAATCAAAG,IntFwd:CTATGCACAGAACCGCTGAG,ExtRev:CGTCGATTATCTTCCTCGAG,IntRev:GAGTCAACAGATGCCAGCTG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Fernández-Majada V, Welz PS, Ermolaeva MA, Schell M, Adam A, Dietlein F, Komander D, Büttner R, Thomas RK, Schumacher B, Pasparakis M.
The tumour suppressor CYLD regulates the p53 DNA damage response.
Nat Commun 2016 7 12508 
[ PubMed ID = 27561390 ] [ RRC reference ]