分離済み変異体

tm3765

Allele Nametm3765
BalanceNot Required
OutCrossNot Accepted
Sequence NameT04D3.3
Gene Namepde-1
Worm BaseAllele Name tm3765
Gene Name pde-1
Sequence T04D3.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 13076/13077-TGTG-13579/13580 (503 bp deletion + 4 bp insertion)
ChromosomeI
Putative gene structurecomplement(join(11323..11339, 11386..11463, 11775..11908, 12032..12138, 12186..12450, 13123..13451, 13554..14049, 14394..14507, 16088..16238, 18468..18615, 18779..18934))
Map position17.92
Balancer
Map position of balancer
Sequence of primersIntFwd:TACTGGTCTAAGCATCACAG,ExtRev:GGCTAGCAGTGTATCTTACA,IntRev:ATCTTACAGGTGCTCTAGGT,ExtFwd:CAACGTTGGCTTGGTAGGTA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Zhao L, Fenk LA, Nilsson L, Amin-Wetzel NP, Ramirez-Suarez NJ, de Bono M, Chen C.
ROS and cGMP signaling modulate persistent escape from hypoxia in Caenorhabditis elegans.
PLoS Biol 2022 20(6) e3001684 
[ PubMed ID = 35727855 ] [ RRC reference ]

Wang D, O'Halloran D, Goodman MB.
GCY-8, PDE-2, and NCS-1 are critical elements of the cGMP-dependent thermotransduction cascade in the AFD neurons responsible for C. elegans thermotaxis.
J Gen Physiol 2013 142(4) 437-49 
[ PubMed ID = 24081984 ] [ RRC reference ]