分離済み変異体

tm3746

Allele Nametm3746
Allele Type通常株
Sequence NameZK455.4
Gene Nameasm-2
Worm BaseAllele Name tm3746
Gene Name asm-2
Sequence ZK455.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 1709/1710-TGATCATTTTTGAA-3111/3112 (1402 bp deletion + 14 bp insertion)
ChromosomeX
Putative gene structurecomplement(join(1215..1341, 1390..1577, 1630..1908, 1991..2078, 2120..2200, 2391..2507, 2568..2737, 2795..2901, 2952..3352, 3965..4104, 4153..4311))
Map position2.96
Balancer
Map position of balancer
Sequence of primersExtFwd:TCGGACCACGATTGAGGTGA,IntFwd:TAGTGTTCTCTGGTGTCGTA,ExtRev:GGGAGCACTCCAAGTCAGCA,IntRev:TCTTGCCTACCTGAAACAGT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Huang M, Hong M, Hou X, Zhu C, Chen D, Chen X, Guang S, Feng X.
H3K9me1/2 methylation limits the lifespan of daf-2 mutants in C. elegans.
Elife 2022 11  
[ PubMed ID = 36125117 ] [ RRC reference ]

Cui M, Wang Y, Cavaleri J, Kelson T, Teng Y, Han M.
Starvation-Induced Stress Response Is Critically Impacted by Ceramide Levels in Caenorhabditis elegans.
Genetics 2017 205(2) 775-785 
[ PubMed ID = 27974500 ] [ RRC reference ]

Hao L, Ben-David O, Babb SM, Futerman AH, Cohen BM, Buttner EA.
Clozapine Modulates Glucosylceramide, Clears Aggregated Proteins, and Enhances ATG8/LC3 in Caenorhabditis elegans.
Neuropsychopharmacology 2017 42(4) 951-962 
[ PubMed ID = 27711049 ] [ RRC reference ]