分離済み変異体

tm3718

Allele Nametm3718
Allele Type通常株
Sequence NameF44C4.3
Gene Namecpr-4
Worm BaseAllele Name tm3718
Gene Name cpr-4
Sequence F44C4.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 8694/8695-TTACCCCAGCTT-9100/9101 (406 bp deletion + 12 bp insertion)
ChromosomeV
Putative gene structurejoin(8016..8018, 8068..9072)
Map position0.11
Balancer
Map position of balancer
Sequence of primersIntRev:TCATGATCCTATCAGTCCAC,IntFwd:CACTCCCGAACTGATAACGA,ExtRev:GATACCACTCCATGCTTCAG,ExtFwd:TAATCCCGGACGCCAATGAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Zheng L, Wu X, Li S, Liu B, Xue D.
Cathepsin B inhibitors block multiple radiation-induced side effects in C. elegans.
Cell Res 2019 29(12) 1042-1045 
[ PubMed ID = 31664165 ] [ RRC reference ]

Peng Y, Zhang M, Zheng L, Liang Q, Li H, Chen JT, Guo H, Yoshina S, Chen YZ, Zhao X, Wu X, Liu B, Mitani S, Yu JS, Xue D.
Cysteine protease cathepsin B mediates radiation-induced bystander effects.
Nature 2017 547(7664) 458-462 
[ PubMed ID = 28723894 ] [ RRC reference ]