分離済み変異体

tm3712

Allele Nametm3712
BalanceNot Required
OutCrossNot Accepted
Sequence NameT20B12.9
Gene Namelgc-50
Worm BaseAllele Name tm3712
Gene Name lgc-50
Sequence T20B12.9
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. C. Bargmann: normal locomotion on food.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 28959/28960-29306/29307 (347 bp deletion)
ChromosomeIII
Putative gene structurecomplement(join(26761..26803, 26939..26994, 27044..27157, 27244..27529, 27833..28125, 28812..28898, 28984..29094, 29385..29421, 29511..29644, 29692..29923, 30249..30286))
Map position-0.73
Balancer
Map position of balancer
Sequence of primersExtFwd:GGGTCATGCTGCTGACTTAC,IntFwd:CCATGACCCTACGCTAAGTA,ExtRev:CTGCAACAACGAATAGCCCT,IntRev:ATCTTTACTAGGGCCAGACA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Zou W, Fan Y, Liu J, Cheng H, Hong H, Al-Sheikh U, Li S, Zhu L, Li R, He L, Tang YQ, Zhao G, Zhang Y, Wang F, Zhan R, Zheng X, Kang L.
Anoctamin-1 is a core component of a mechanosensory anion channel complex in C. elegans.
Nat Commun 2025 16(1) 1680 
[ PubMed ID = 39956854 ] [ RRC reference ]

White AM, Bauer AD, Faumont S, Lockery SR.
Behavioral and genetic analysis of the effects of the psychedelic 2,5-dimethoxy-4-iodoamphetamine (DOI) in C. elegans.
PLoS One 2025 20(8) e0329538 
[ PubMed ID = 40857291 ] [ RRC reference ]

Morud J, Hardege I, Liu H, Wu T, Choi MK, Basu S, Zhang Y, Schafer WR.
Deorphanization of novel biogenic amine-gated ion channels identifies a new serotonin receptor for learning.
Curr Biol 2021 31(19) 4282-4292.e6 
[ PubMed ID = 34388373 ] [ RRC reference ]