分離済み変異体

tm3690

Allele Nametm3690
BalanceNot Required
OutCrossNot Accepted
Sequence NameZK20.3
Gene Namerad-23
Worm BaseAllele Name tm3690
Gene Name rad-23
Sequence ZK20.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 29968/29969-30400/30401 (432 bp deletion)
ChromosomeII
Putative gene structurecomplement(join(30077..30088, 30143..30946, 30996..31079, 31126..31198, 31319..31464))
Map position3.82
Balancer
Map position of balancer
Sequence of primersExtRev:GAGCCTTCTCAACTGCGACA,IntRev:GCCCACACAGCCAGAAGATT,ExtFwd:GCGGGTGACAATCAGCACAT,IntFwd:TAGACAAAGGGCAATCGAGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Eck RJ, Stair JG, Kraemer BC, Liachko NF.
Simple models to understand complex disease: 10 years of progress from Caenorhabditis elegans models of amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Front Neurosci 2023 17 1300705 
[ PubMed ID = 38239833 ] [ RRC reference ]

Jablonski AM, Lamitina T, Liachko NF, Sabatella M, Lu J, Zhang L, Ostrow LW, Gupta P, Wu CY, Doshi S, Mojsilovic-Petrovic J, Lans H, Wang J, Kraemer B, Kalb RG.
Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance.
J Neurosci 2015 35(42) 14286-306 
[ PubMed ID = 26490867 ] [ RRC reference ]

Lans H, Vermeulen W.
Nucleotide Excision Repair in Caenorhabditis elegans.
Mol Biol Int 2011 2011 542795 
[ PubMed ID = 22091407 ] [ RRC reference ]