Home > 分離済み変異体 > tm3688

分離済み変異体

Allele Name		tm3688
Balance		Completed
OutCross		Not Accepted
Sequence Name		C41C4.6
Gene Name		ulp-4
Worm Base	Allele Name	tm3688 (x1)
	Gene Name	ulp-4
	Sequence	C41C4.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		32717/32718-32929/32930 (212 bp deletion)
Chromosome		II
Putative gene structure		join(30537..30684, 30734..30915, 31080..31181, 32818..33366, 34782..34829)
Map position		0.71
Balancer		mIn1,mIn1 [e128 mIs14]
Map position of balancer
Sequence of primers		ExtRev:ATTCGACAAGCGGACGCCAA,IntFwd:CCGAACGGCGTAACTCGTAG,ExtFwd:GCACGCACCTCCCATACTCT,IntRev:GCTCTGTTCGTGGATAGTGA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Zhang Y, Samuelson AV. Aging impairs the antiviral defense in Caenorhabditis elegans due to loss of DRH-1/RIG-I deSUMOylation by ULP-4/SENP7. EMBO Rep 2025 26(22) 5459-5482  [ PubMed ID = 41039133 ] [ RRC reference ] Cornwell AB, Zhang Y, Thondamal M, Johnson DW, Thakar J, Samuelson AV. The C. elegans Myc-family of transcription factors coordinate a dynamic adaptive response to dietary restriction. Geroscience 2024 46(5) 4827-4854  [ PubMed ID = 38878153 ] [ RRC reference ] Cornwell A, Zhang Y, Thondamal M, Johnson DW, Thakar J, Samuelson AV. The C. elegans Myc-family of transcription factors coordinate a dynamic adaptive response to dietary restriction. bioRxiv 2023    [ PubMed ID = 38045350 ] [ RRC reference ] Sapir A, Tsur A, Koorman T, Ching K, Mishra P, Bardenheier A, Podolsky L, Bening-Abu-Shach U, Boxem M, Chou TF, Broday L, Sternberg PW. Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging. Proc Natl Acad Sci U S A 2014 111(37) E3880-9  [ PubMed ID = 25187565 ] [ RRC reference ]