分離済み変異体

tm3671

Allele Name

tm3671

Balance

Completed

OutCross

Not Accepted

Sequence Name

Y48A6C.5

Gene Name

pha-1

Worm Base

Allele Name

tm3671 (x1)

Gene Name

pha-1

Sequence

Y48A6C.5

Phenotype

lethal or sterile.

Mutation site

31888/31889-32091/32092 (203 bp deletion)

Chromosome

III

Putative gene structure

join(31284..31331, 31944..32335, 32388..32509, 32579..32747, 34723..35467)

Map position

6.14

Balancer

hT2 [bli-4(e937) let-? qIs48]

Map position of balancer

Sequence of primers

ExtFwd:CGTTGCTCGATGATTTCTCC,IntFwd:CCTTGCGAATAACATAGCAG,ExtRev:CGGTTGTCGCGCACTACTGA,IntRev:GCACTACTGAATCAGAGTCT

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Boopathi B, Topalidou I, Kelley M, Meadows SM, Funk O, Ailion M, Fay DS.
Pathways that affect anterior morphogenesis in C. elegans embryos.
bioRxiv 2023
[ PubMed ID = 37163004 ] [ RRC reference ]

Kelley M, Yochem J, Krieg M, Calixto A, Heiman MG, Kuzmanov A, Meli V, Chalfie M, Goodman MB, Shaham S, Frand A, Fay DS.
FBN-1, a fibrillin-related protein, is required for resistance of the epidermis to mechanical deformation during C. elegans embryogenesis.
Elife 2015 4
[ PubMed ID = 25798732 ] [ RRC reference ]

Kuzmanov A, Yochem J, Fay DS.
Analysis of PHA-1 reveals a limited role in pharyngeal development and novel functions in other tissues.
Genetics 2014 198(1) 259-68
[ PubMed ID = 25009149 ] [ RRC reference ]

Polley SR, Kuzmanov A, Kuang J, Karpel J, Lažetić V, Karina EI, Veo BL, Fay DS.
Implicating SCF complexes in organogenesis in Caenorhabditis elegans.
Genetics 2014 196(1) 211-23
[ PubMed ID = 24214340 ] [ RRC reference ]

Fay DS, Polley SR, Kuang J, Kuzmanov A, Hazel JW, Mani K, Veo BL, Yochem J.
A regulatory module controlling pharyngeal development and function in Caenorhabditis elegans.
Genetics 2012 191(3) 827-43
[ PubMed ID = 22542967 ] [ RRC reference ]

Mani K, Fay DS.
A mechanistic basis for the coordinated regulation of pharyngeal morphogenesis in Caenorhabditis elegans by LIN-35/Rb and UBC-18-ARI-1.
PLoS Genet 2009 5(6) e1000510
[ PubMed ID = 19521497 ] [ RRC reference ]