分離済み変異体

tm3643

Allele Nametm3643
BalanceNot Required
OutCrossNot Accepted
Sequence NameF17H10.3
Gene Namesnx-17
Worm BaseAllele Name tm3643
Gene Name snx-17
Sequence F17H10.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. Z. Zhou: no persistent cell corpses.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 11749/11750-CGTAATTT-11991/11992 (242 bp deletion + 8 bp insertion)
ChromosomeX
Putative gene structurecomplement(join(10053..10109, 10169..10279, 10462..10599, 10646..10786, 10834..10974, 11161..11332, 11381..11480, 11534..11663, 11993..12103, 12157..12221, 12267..12462, 12602..12736, 15676..15801))
Map position10.23
Balancer
Map position of balancer
Sequence of primersIntRev:CCGGATACGAAGACACTAGT,ExtRev:CCAGCGGATAAGACAACGTT,IntFwd:TGCGGAGGAACTGTAACTAA,ExtFwd:CGTAGGAGTATGTCGAGAGT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Tian Y, Kang Q, Shi X, Wang Y, Zhang N, Ye H, Xu Q, Xu T, Zhang R.
SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
PLoS Genet 2021 17(6) e1009607 
[ PubMed ID = 34081703 ] [ RRC reference ]

Lu N, Shen Q, Mahoney TR, Liu X, Zhou Z.
Three sorting nexins drive the degradation of apoptotic cells in response to PtdIns(3)P signaling.
Mol Biol Cell 2011 22(3) 354-74 
[ PubMed ID = 21148288 ] [ RRC reference ]