分離済み変異体

tm3618

Allele Name

tm3618

Balance

Not Required

OutCross

Not Accepted

Sequence Name

C06E2.8

Gene Name

ins-9

Worm Base

Allele Name

tm3618

Gene Name

ins-9

Sequence

C06E2.8

Phenotype

homozygous viable. Dr. Q.L. Ch'ng: non-Unc, non-Pvl, non-Lon, non-Sma, non-Dpy.

Mutation site

15546/15547-CACACAGCTTAGAGAGATCCTGTTCCGT-15757/15758 (211 bp deletion + 28 bp insertion)

Chromosome

Putative gene structure

complement(join(15699..15785, 15832..16101))

Map position

0.44

Balancer

Map position of balancer

Sequence of primers

IntRev:AGGAGTGAAACGATGATCGT,ExtRev:ATGTCCCGCCCCAAATGTTG,IntFwd:CAGATGGCTCGTAGGGACAA,ExtFwd:GTATTAGGTAGTAGGCTGTC

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Zhang MG, Seyedolmohadesin M, Mercado SH, Tauffenberger A, Park H, Finnen N, Schroeder FC, Venkatachalam V, Sternberg PW.
Sensory integration of food and population density during the diapause exit decision involves insulin-like signaling in Caenorhabditis elegans.
Proc Natl Acad Sci U S A 2024 121(40) e2405391121
[ PubMed ID = 39316052 ] [ RRC reference ]

Zhang MG, Seyedolmohadesin M, Hawk S, Park H, Finnen N, Schroeder F, Venkatachalam V, Sternberg PW.
Sensory integration of food availability and population density during the diapause exit decision involves insulin-like signaling in Caenorhabditis elegans.
bioRxiv 2024
[ PubMed ID = 38586049 ] [ RRC reference ]

Delaney CE, Chen AT, Graniel JV, Dumas KJ, Hu PJ.
A histone H4 lysine 20 methyltransferase couples environmental cues to sensory neuron control of developmental plasticity.
Development 2017 144(7) 1273-1282
[ PubMed ID = 28209779 ] [ RRC reference ]

Lee D, Lee H, Kim N, Lim DS, Lee J.
Regulation of a hitchhiking behavior by neuronal insulin and TGF-β signaling in the nematode Caenorhabditis elegans.
Biochem Biophys Res Commun 2017 484(2) 323-330
[ PubMed ID = 28131836 ] [ RRC reference ]

Chen Y, Baugh LR.
Ins-4 and daf-28 function redundantly to regulate C. elegans L1 arrest.
Dev Biol 2014 394(2) 314-26
[ PubMed ID = 25128585 ] [ RRC reference ]

Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q.
An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology.
PLoS Genet 2014 10(3) e1004225
[ PubMed ID = 24675767 ] [ RRC reference ]