分離済み変異体

tm3617

Allele Nametm3617
BalanceNot Required
OutCrossNot Accepted
Sequence NameC32E12.2
Gene Namepde-5
Worm BaseAllele Name tm3617
Gene Name pde-5
Sequence C32E12.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 964/965-AAAATATAAACTTAACGCTCTCA-1882/1883 (918 bp deletion + 23 bp insertion)
ChromosomeI
Putative gene structurejoin(972..1126, 1184..1438, 1501..1587, 1633..1786, 1997..2325, 2371..2572)
Map position-0.28
Balancer
Map position of balancer
Sequence of primersIntFwd:GGGGATGATCCGATGACTAT,ExtFwd:GTACGGTAGGATACTACGTC,IntRev:GGCTTGTATGGATTTCAGTC,ExtRev:ACGTAGAGGGCCAACGCCTA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Ohta A, Ujisawa T, Sonoda S, Kuhara A.
Light and pheromone-sensing neurons regulates cold habituation through insulin signalling in Caenorhabditis elegans.
Nat Commun 2014 5 4412 
[ PubMed ID = 25048458 ] [ RRC reference ]

Wang D, O'Halloran D, Goodman MB.
GCY-8, PDE-2, and NCS-1 are critical elements of the cGMP-dependent thermotransduction cascade in the AFD neurons responsible for C. elegans thermotaxis.
J Gen Physiol 2013 142(4) 437-49 
[ PubMed ID = 24081984 ] [ RRC reference ]