分離済み変異体

tm361

Allele Nametm361
Allele Type通常株
Sequence NameC18A3.5
Gene NameC18A3.5
Worm BaseAllele Name tm361
Gene Name C18A3.5
Sequence C18A3.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. T. Schedl: no germline phenotype. Dr. H. Zhang: fertile and normal locomotion.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 12290/12291-12869/12870 (579 bp deletion)
ChromosomeII
Putative gene structurecomplement(join(11415..11699, 11746..11930, 12009..12429, 12637..12732, 12870..12931, 13011..13165, 13238..13380))
Map position-0.96
Balancer
Map position of balancer
Sequence of primersIntRev:GTACTAGACGTCCAGTTCTT,ExtFwd:GGGTGGAACTTGGAATTAAG,ExtRev:GCTAGGAATTTTGGCGATAG,IntFwd:GGGCAATAGGGTCACATATA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Andrusiak MG, Sharifnia P, Lyu X, Wang Z, Dickey AM, Wu Z, Chisholm AD, Jin Y.
Inhibition of Axon Regeneration by Liquid-like TIAR-2 Granules.
Neuron 2019 104(2) 290-304.e8 
[ PubMed ID = 31378567 ] [ RRC reference ]

Huelgas-Morales G, Silva-García CG, Salinas LS, Greenstein D, Navarro RE.
The Stress Granule RNA-Binding Protein TIAR-1 Protects Female Germ Cells from Heat Shock in Caenorhabditis elegans.
G3 (Bethesda) 2016 6(4) 1031-47 
[ PubMed ID = 26865701 ] [ RRC reference ]

Silva-García CG, Estela Navarro R.
The C. elegans TIA-1/TIAR homolog TIAR-1 is required to induce germ cell apoptosis.
Genesis 2013 51(10) 690-707 
[ PubMed ID = 23913578 ] [ RRC reference ]

Rousakis A, Vlanti A, Borbolis F, Roumelioti F, Kapetanou M, Syntichaki P.
Diverse functions of mRNA metabolism factors in stress defense and aging of Caenorhabditis elegans.
PLoS One 2014 9(7) e103365 
[ PubMed ID = 25061667 ] [ RRC reference ]