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分離済み変異体

Allele Name		tm3577
Balance		Not Required
OutCross		Not Accepted
Sequence Name		ZC482.1
Gene Name		gab-1
Worm Base	Allele Name	tm3577
	Gene Name	gab-1
	Sequence	ZC482.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. C. Bargmann: reduced locomotion on food. Dr. I. Mori: normal thermotaxix at 20C.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		24302/24303-TATATATTTGACGCGCAAAAAAAA-24818/24819 (516 bp deletion + 24 bp insertion)
Chromosome		III
Putative gene structure		complement(join(21501..21540, 22596..22763, 22809..23002, 23056..23139, 23194..23275, 23317..23417, 24483..24865, 25262..25464, 26468..26574, 26640..26707, 28726..28862, 29152..29237))
Map position		18.58
Balancer
Map position of balancer
Sequence of primers		ExtFwd:AACGCGCCAAAACTCGGCTA,IntFwd:GTGTGTAATACGGGACCACA,ExtRev:CCCCACCGCTGCACTAAACT,IntRev:AACCGTGGCAAGCCTTCTAG
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Zou W, Fan Y, Liu J, Cheng H, Hong H, Al-Sheikh U, Li S, Zhu L, Li R, He L, Tang YQ, Zhao G, Zhang Y, Wang F, Zhan R, Zheng X, Kang L. Anoctamin-1 is a core component of a mechanosensory anion channel complex in C. elegans. Nat Commun 2025 16(1) 1680  [ PubMed ID = 39956854 ] [ RRC reference ] McDiarmid TA, Belmadani M, Liang J, Meili F, Mathews EA, Mullen GP, Hendi A, Wong WR, Rand JB, Mizumoto K, Haas K, Pavlidis P, Rankin CH. Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation. Proc Natl Acad Sci U S A 2020 117(1) 656-667  [ PubMed ID = 31754030 ] [ RRC reference ]