Home > 分離済み変異体 > tm3572

分離済み変異体

Allele Name		tm3572
Balance		Not Required
OutCross		Not Accepted
Sequence Name		E03D2.2
Gene Name		nlp-9
Worm Base	Allele Name	tm3572
	Gene Name	nlp-9
	Sequence	E03D2.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		1749/1750-TT-1859/1860 (110 bp deletion + 2 bp insertion)
Chromosome		V
Putative gene structure		join(1058..1112, 1757..1817, 1866..2018, 2069..2128, 3230..3290)
Map position		-6.19
Balancer
Map position of balancer
Sequence of primers		IntFwd:AGATGTGTGGTCTCCGCTAA,ExtRev:TCTGTTATCCGGCAACGTCA,IntRev:TACTTACCGTTCCAAGTACG,ExtFwd:CGCTGCATCTCTTGACTTAG
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Shao J, Liewald JF, Steuer Costa W, Ruse C, Gruber J, Djamshedzad MS, Gebhardt W, Gottschalk A. Loss of neuropeptidergic regulation of cholinergic transmission induces homeostatic compensation in muscle cells to preserve synaptic strength. PLoS Biol 2025 23(5) e3003171  [ PubMed ID = 40338987 ] [ RRC reference ] Clark T, Hapiak V, Oakes M, Mills H, Komuniecki R. Monoamines differentially modulate neuropeptide release from distinct sites within a single neuron pair. PLoS One 2018 13(5) e0196954  [ PubMed ID = 29723289 ] [ RRC reference ] Harris G, Shen Y, Ha H, Donato A, Wallis S, Zhang X, Zhang Y. Dissecting the signaling mechanisms underlying recognition and preference of food odors. J Neurosci 2014 34(28) 9389-403  [ PubMed ID = 25009271 ] [ RRC reference ] Hapiak V, Summers P, Ortega A, Law WJ, Stein A, Komuniecki R. Neuropeptides amplify and focus the monoaminergic inhibition of nociception in Caenorhabditis elegans. J Neurosci 2013 33(35) 14107-16  [ PubMed ID = 23986246 ] [ RRC reference ] Stawicki TM, Takayanagi-Kiya S, Zhou K, Jin Y. Neuropeptides function in a homeostatic manner to modulate excitation-inhibition imbalance in C. elegans. PLoS Genet 2013 9(5) e1003472  [ PubMed ID = 23658528 ] [ RRC reference ] Mills H, Wragg R, Hapiak V, Castelletto M, Zahratka J, Harris G, Summers P, Korchnak A, Law W, Bamber B, Komuniecki R. Monoamines and neuropeptides interact to inhibit aversive behaviour in Caenorhabditis elegans. EMBO J 2012 31(3) 667-78  [ PubMed ID = 22124329 ] [ RRC reference ]