Home > 分離済み変異体 > tm3543

分離済み変異体

Allele Name		tm3543
Allele Type		通常株
Sequence Name		F33G12.4
Gene Name		lrr-1
Worm Base	Allele Name	tm3543
	Gene Name	lrr-1
	Sequence	F33G12.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		12446/12447-12934/12935 (488 bp deletion)
Chromosome		II
Putative gene structure		complement(join(11426..11519, 11626..11841, 11894..12019, 12428..12639, 12689..13045, 13098..13181, 13232..13393, 13447..13557))
Map position		-2.59
Balancer
Map position of balancer
Sequence of primers		ExtFwd:CCGATCACGTCGACAGAATT,ExtRev:CGTGGCCGGTGACAAAACTG,IntFwd:CGAATATGCCGAAGTCTGAC,IntRev:AGCCGCCAATTATTCTCGAC
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Matty MA, Lau HE, Haley JA, Singh A, Chakraborty A, Kono K, Reddy KC, Hansen M, Chalasani SH. Intestine-to-neuronal signaling alters risk-taking behaviors in food-deprived Caenorhabditis elegans. PLoS Genet 2022 18(5) e1010178  [ PubMed ID = 35511794 ] [ RRC reference ] Ossareh-Nazari B, Katsiarimpa A, Merlet J, Pintard L. RNAi-Based Suppressor Screens Reveal Genetic Interactions Between the CRL2LRR-1 E3-Ligase and the DNA Replication Machinery in Caenorhabditis elegans. G3 (Bethesda) 2016 6(10) 3431-3442  [ PubMed ID = 27543292 ] [ RRC reference ] Sonneville R, Moreno SP, Knebel A, Johnson C, Hastie CJ, Gartner A, Gambus A, Labib K. CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis. Nat Cell Biol 2017 19(5) 468-479  [ PubMed ID = 28368371 ] [ RRC reference ] Merlet J, Burger J, Tavernier N, Richaudeau B, Gomes JE, Pintard L. The CRL2LRR-1 ubiquitin ligase regulates cell cycle progression during C. elegans development. Development 2010 137(22) 3857-66  [ PubMed ID = 20978077 ] [ RRC reference ] Burger J, Merlet J, Tavernier N, Richaudeau B, Arnold A, Ciosk R, Bowerman B, Pintard L. CRL2(LRR-1) E3-ligase regulates proliferation and progression through meiosis in the Caenorhabditis elegans germline. PLoS Genet 2013 9(3) e1003375  [ PubMed ID = 23555289 ] [ RRC reference ]