分離済み変異体

tm3526

Allele Name

tm3526

Balance

Not Required

OutCross

Not Accepted

Sequence Name

Y51H4A.12

Gene Name

set-26

Worm Base

Allele Name

tm3526

Gene Name

set-26

Sequence

Y51H4A.12

Phenotype

homozygous viable. Dr. S.S. Lee: deletion confirmed.

Mutation site

179494/179495-179851/179852 (357 bp deletion)

Chromosome

Putative gene structure

complement(join(175289..175332, 175464..175728, 176384..177177, 177711..177984, 178467..180302, 181241..182147, 183042..183382, 183470..183840, 183892..183997))

Map position

15.14

Balancer

Map position of balancer

Sequence of primers

ExtFwd:AAGACGAGACCCTGGCAATG,IntFwd:TCGAATCGAAACCACGCCAG,ExtRev:CCGCCGAACTTCCTCCTCAA,IntRev:AAGCCTCCGACGCTCCTCAT

Distributed lab

Depositor

Dr. S. Mitani

References

Please submit your publication

Carvalho CA, Abu-Shach UB, Raju A, Vershinin Z, Levy D, Boxem M, Broday L.
SUMO-mediated regulation of H3K4me3 reader SET-26 controls germline development in C. elegans.
PLoS Biol 2025 23(1) e3002980
[ PubMed ID = 39761316 ] [ RRC reference ]

Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69
[ PubMed ID = 38164610 ] [ RRC reference ]

Kalinava N, Ni JZ, Peterman K, Chen E, Gu SG.
Decoupling the downstream effects of germline nuclear RNAi reveals that H3K9me3 is dispensable for heritable RNAi and the maintenance of endogenous siRNA-mediated transcriptional silencing in Caenorhabditis elegans.
Epigenetics Chromatin 2017 10 6
[ PubMed ID = 28228846 ] [ RRC reference ]

Greer EL, Beese-Sims SE, Brookes E, Spadafora R, Zhu Y, Rothbart SB, Aristizábal-Corrales D, Chen S, Badeaux AI, Jin Q, Wang W, Strahl BD, Colaiácovo MP, Shi Y.
A histone methylation network regulates transgenerational epigenetic memory in C. elegans.
Cell Rep 2014 7(1) 113-26
[ PubMed ID = 24685137 ] [ RRC reference ]