分離済み変異体

tm3524

Allele Nametm3524
Allele Type通常株
Sequence NameC16E9.4
Gene Nameinx-1
Worm BaseAllele Name tm3524
Gene Name inx-1
Sequence C16E9.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. C. Hunter: normal growth and developement at 20C. Dr. C-F. Chuang: normal AWC signaling.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 14424/14425-14662/14663 (238 bp deletion)
ChromosomeX
Putative gene structurecomplement(join(10133..11266, 12265..12353, 14171..14269, 14315..14413, 14470..14637, 14682..14918, 14967..15091, 15448..15557, 15604..15739, 15808..15964, 17792..17911, 22717..22792))
Map position-1.93
Balancer
Map position of balancer
Sequence of primersExtFwd:TCGTCGGCCACTCATTTGAC,IntFwd:CTTATTCGATCTGTCGTGGT,ExtRev:GGCCTTGATCATGAAAGCTG,IntRev:TGTGTTCGGAACGCAGCGTG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Jiang J, Su Y, Zhang R, Li H, Tao L, Liu Q.
C. elegans enteric motor neurons fire synchronized action potentials underlying the defecation motor program.
Nat Commun 2022 13(1) 2783 
[ PubMed ID = 35589790 ] [ RRC reference ]

Choi U, Wang H, Hu M, Kim S, Sieburth D.
Presynaptic coupling by electrical synapses coordinates a rhythmic behavior by synchronizing the activities of a neuron pair.
Proc Natl Acad Sci U S A 2021 118(20)  
[ PubMed ID = 33972428 ] [ RRC reference ]

Hori S, Oda S, Suehiro Y, Iino Y, Mitani S.
OFF-responses of interneurons optimize avoidance behaviors depending on stimulus strength via electrical synapses.
PLoS Genet 2018 14(6) e1007477 
[ PubMed ID = 29939997 ] [ RRC reference ]

Jang H, Levy S, Flavell SW, Mende F, Latham R, Zimmer M, Bargmann CI.
Dissection of neuronal gap junction circuits that regulate social behavior in Caenorhabditis elegans.
Proc Natl Acad Sci U S A 2017 114(7) E1263-E1272 
[ PubMed ID = 28143932 ] [ RRC reference ]

Liu P, Chen B, Altun ZF, Gross MJ, Shan A, Schuman B, Hall DH, Wang ZW.
Six innexins contribute to electrical coupling of C. elegans body-wall muscle.
PLoS One 2013 8(10) e76877 
[ PubMed ID = 24130800 ] [ RRC reference ]