Home > 分離済み変異体 > tm3506

分離済み変異体

Allele Name		tm3506
Balance		Not Required
OutCross		Not Accepted
Sequence Name		ZC196.7
Gene Name		glr-5
Worm Base	Allele Name	tm3506
	Gene Name	glr-5
	Sequence	ZC196.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. I. Mori: normal thermotaxix at 20C.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		6487/6488-6732/6733 (245 bp deletion)
Chromosome		V
Putative gene structure		join(3767..3848, 4081..4230, 4284..4375, 4420..4579, 4766..5490, 5770..6292, 6338..6451, 6521..6649, 6693..7085, 7159..7252, 7330..7558, 7611..7718)
Map position		1.56
Balancer
Map position of balancer
Sequence of primers		IntFwd:CCTGAACTTCGAGACATGCA,ExtRev:TGCGGCTCCTCTGAAATGCT,ExtFwd:ACACGACTGTAGTGCGTGGT,IntRev:TGCGAGTGCGATTCCATAAC
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Kramer TS, Wan FK, Pugliese SM, Atanas AA, Hiser AW, Luo J, Bueno E, Flavell SW. Neural Sequences Underlying Directed Turning in C. elegans. bioRxiv 2024    [ PubMed ID = 39149398 ] [ RRC reference ] Lin C, Shan Y, Wang Z, Peng H, Li R, Wang P, He J, Shen W, Wu Z, Guo M. Molecular and circuit mechanisms underlying avoidance of rapid cooling stimuli in C. elegans. Nat Commun 2024 15(1) 297  [ PubMed ID = 38182628 ] [ RRC reference ] Liu H, Wu JJ, Li R, Wang PZ, Huang JH, Xu Y, Zhao JL, Wu PP, Li SJ, Wu ZX. Disexcitation in the ASH/RIM/ADL negative feedback circuit fine-tunes hyperosmotic sensation and avoidance in Caenorhabditis elegans. Front Mol Neurosci 2023 16 1101628  [ PubMed ID = 37008778 ] [ RRC reference ] Motomura H, Ioroi M, Murakami K, Kuhara A, Ohta A. Head-tail-head neural wiring underlies gut fat storage in Caenorhabditis elegans temperature acclimation. Proc Natl Acad Sci U S A 2022 119(32) e2203121119  [ PubMed ID = 35914124 ] [ RRC reference ] Choi W, Ryu SE, Cheon Y, Park YJ, Kim S, Kim E, Koo J, Choi H, Moon C, Kim K. A single chemosensory GPCR is required for a concentration-dependent behavioral switching in C. elegans. Curr Biol 2022 32(2) 398-411.e4  [ PubMed ID = 34906353 ] [ RRC reference ] Wang M, Witvliet D, Wu M, Kang L, Shao Z. Temperature regulates synaptic subcellular specificity mediated by inhibitory glutamate signaling. PLoS Genet 2021 17(1) e1009295  [ PubMed ID = 33428618 ] [ RRC reference ] Wen X, Chen YH, Li R, Ge MH, Yin SW, Wu JJ, Huang JH, Liu H, Wang PZ, Gross E, Wu ZX. Signal Decoding for Glutamate Modulating Egg Laying Oppositely in Caenorhabditiselegans under Varied Environmental Conditions. iScience 2020 23(10) 101588  [ PubMed ID = 33089099 ] [ RRC reference ] Bhatla N, Droste R, Sando SR, Huang A, Horvitz HR. Distinct Neural Circuits Control Rhythm Inhibition and Spitting by the Myogenic Pharynx of C. elegans. Curr Biol 2015 25(16) 2075-89  [ PubMed ID = 26212880 ] [ RRC reference ] Hardaway JA, Sturgeon SM, Snarrenberg CL, Li Z, Xu XZ, Bermingham DP, Odiase P, Spencer WC, Miller DM 3rd, Carvelli L, Hardie SL, Blakely RD. Glial Expression of the Caenorhabditis elegans Gene swip-10 Supports Glutamate Dependent Control of Extrasynaptic Dopamine Signaling. J Neurosci 2015 35(25) 9409-23  [ PubMed ID = 26109664 ] [ RRC reference ]