分離済み変異体

tm3505

Allele Nametm3505
BalanceNot Required
OutCrossNot Accepted
Sequence NameY51H4A.12
Gene Nameset-26
Worm BaseAllele Name tm3505
Gene Name set-26
Sequence Y51H4A.12
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. S.S. Lee: deletion confirmed.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 179760/179761-180143/180144 (383 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(175289..175332, 175464..175728, 176384..177177, 177711..177984, 178467..180302, 181241..182147, 183042..183382, 183470..183840, 183892..183997))
Map position15.14
Balancer
Map position of balancer
Sequence of primersIntRev:AAGCCTCCGACGCTCCTCAT,ExtRev:CCGCCGAACTTCCTCCTCAA,IntFwd:TCGAATCGAAACCACGCCAG,ExtFwd:AAGACGAGACCCTGGCAATG
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Carvalho CA, Abu-Shach UB, Raju A, Vershinin Z, Levy D, Boxem M, Broday L.
SUMO-mediated regulation of H3K4me3 reader SET-26 controls germline development in C. elegans.
PLoS Biol 2025 23(1) e3002980 
[ PubMed ID = 39761316 ] [ RRC reference ]

Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Ni Z, Ebata A, Alipanahiramandi E, Lee SS.
Two SET domain containing genes link epigenetic changes and aging in Caenorhabditis elegans.
Aging Cell 2012 11(2) 315-25 
[ PubMed ID = 22212395 ] [ RRC reference ]