Home > 分離済み変異体 > tm3498

分離済み変異体

Allele Name		tm3498
Balance		Not Required
OutCross		Not Accepted
Sequence Name		T08G5.12
Gene Name		ins-10
Worm Base	Allele Name	tm3498
	Gene Name	ins-10
	Sequence	T08G5.12
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. Q.L. Ch'ng: normal locomotion, egg-laying and body shape.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		16927/16928-TTGA-17401/17402 (474 bp deletion + 4 bp insertion)
Chromosome		V
Putative gene structure		join(17340..17523, 17580..17653)
Map position		6.09
Balancer
Map position of balancer
Sequence of primers		IntFwd:TGTCGTCTTGGGTCCTCGCA,ExtFwd:AGGGGGTGTGTGACTATCAT,IntRev:AGTACGGTACCTAGTACCTG,ExtRev:GGATGGTCGATTGGCACATC
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Matty MA, Lau HE, Haley JA, Singh A, Chakraborty A, Kono K, Reddy KC, Hansen M, Chalasani SH. Intestine-to-neuronal signaling alters risk-taking behaviors in food-deprived Caenorhabditis elegans. PLoS Genet 2022 18(5) e1010178  [ PubMed ID = 35511794 ] [ RRC reference ] Lee D, Lee H, Kim N, Lim DS, Lee J. Regulation of a hitchhiking behavior by neuronal insulin and TGF-β signaling in the nematode Caenorhabditis elegans. Biochem Biophys Res Commun 2017 484(2) 323-330  [ PubMed ID = 28131836 ] [ RRC reference ] Chen X, Chalfie M. Modulation of C. elegans touch sensitivity is integrated at multiple levels. J Neurosci 2014 34(19) 6522-36  [ PubMed ID = 24806678 ] [ RRC reference ] Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q. An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology. PLoS Genet 2014 10(3) e1004225  [ PubMed ID = 24675767 ] [ RRC reference ] Hung WL, Hwang C, Gao S, Liao EH, Chitturi J, Wang Y, Li H, Stigloher C, Bessereau JL, Zhen M. Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development. EMBO J 2013 32(12) 1745-60  [ PubMed ID = 23665919 ] [ RRC reference ]