分離済み変異体

tm349

Allele Nametm349
BalanceCompleted
OutCrossNot Accepted
Sequence NameB0350.2
Gene Nameunc-44
Worm BaseAllele Name tm349 (x1)
Gene Name unc-44
Sequence B0350.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" Let or Ste.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 25508/25509-26167/26168 (659 bp deletion)
ChromosomeIV
Putative gene structurea.1=join(21831..22631, 22795..22944, 23506..23757) ; b.1=join(17346..17698, 18711..18843, 18890..20732, 20844..21021, 21072..21256, 21369..21657); c.1=join(2932..3039, 11833..12142, 12528..13021, 13876..14693, 15050..15691, 15865..15977, 16147..16437, 17346..17698, 18711..18843, 18890..20732, 20844..21021, 21072..21256, 21369..21446, 22795..22944, 23506..23747)
Map position2.91
BalancernT1,nT1 [qIs51]
Map position of balancer
Sequence of primersIntRev:TTCCGATTCAACATGGGATG,ExtFwd:GGAATGTCGAGTCTGCTTAT,IntFwd:GTTGAAACCGATCGCCGTGA,ExtRev:GAGACTCAAGAACCTGACGT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
He L, Kooistra R, Das R, Oudejans E, van Leen E, Ziegler J, Portegies S, de Haan B, van Regteren Altena A, Stucchi R, Altelaar AM, Wieser S, Krieg M, Hoogenraad CC, Harterink M.
Cortical anchoring of the microtubule cytoskeleton is essential for neuron polarity.
Elife 2020 9  
[ PubMed ID = 32293562 ] [ RRC reference ]

Chen F, Chisholm AD, Jin Y.
Tissue-specific regulation of alternative polyadenylation represses expression of a neuronal ankyrin isoform in C. elegans epidermal development.
Development 2017 144(4) 698-707 
[ PubMed ID = 28087624 ] [ RRC reference ]

Chen F, Zhou Y, Qi YB, Khivansara V, Li H, Chun SY, Kim JK, Fu XD, Jin Y.
Context-dependent modulation of Pol II CTD phosphatase SSUP-72 regulates alternative polyadenylation in neuronal development.
Genes Dev 2015 29(22) 2377-90 
[ PubMed ID = 26588990 ] [ RRC reference ]