Home > 分離済み変異体 > tm3473

分離済み変異体

Allele Name		tm3473
Balance		Completed
OutCross		Not Accepted
Sequence Name		Y48B6A.3
Gene Name		xrn-2
Worm Base	Allele Name	tm3473 (x1)
	Gene Name	xrn-2
	Sequence	Y48B6A.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		7507/7508-7785/7786 (278 bp deletion)
Chromosome		II
Putative gene structure		join(5439..5726, 6057..6347, 7256..7931, 12071..12464, 13895..14318, 14963..15568)
Map position		22.4
Balancer		mnC1 [dpy-10(e128) unc52(e444) nIs190 let-?]
Map position of balancer
Sequence of primers		IntFwd:ACGCGAATGTTCCCGGCGAA,ExtFwd:GATCATCCTCTCCGACGCGA,IntRev:CCGGTCTCCGGTTTTCATAG,ExtRev:CATACCTTCGGTTTTCCGGT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Mazzetto M, Gonzalez LE, Sanchez N, Reinke V. Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis. Genome Res 2024 34(1) 57-69  [ PubMed ID = 38164610 ] [ RRC reference ] Miki TS, Rüegger S, Gaidatzis D, Stadler MB, Großhans H. Engineering of a conditional allele reveals multiple roles of XRN2 in Caenorhabditis elegans development and substrate specificity in microRNA turnover. Nucleic Acids Res 2014 42(6) 4056-67  [ PubMed ID = 24445807 ] [ RRC reference ] Miki TS, Richter H, Rüegger S, Großhans H. PAXT-1 promotes XRN2 activity by stabilizing it through a conserved domain. Mol Cell 2014 53(2) 351-60  [ PubMed ID = 24462208 ] [ RRC reference ] C. elegans Deletion Mutant Consortium. large-scale screening for targeted knockouts in the Caenorhabditis elegans genome. G3 (Bethesda) 2012 2(11) 1415-25  [ PubMed ID = 23173093 ] [ RRC reference ]