Home > 分離済み変異体 > tm3463

分離済み変異体

Allele Name		tm3463
Allele Type		通常株
Sequence Name		F21H12.1
Gene Name		rbbp-5
Worm Base	Allele Name	tm3463
	Gene Name	rbbp-5
	Sequence	F21H12.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr.J.M. Schumacher: Sck, Evl, reduced brood size. Dr. O. Hobert: ASE development defective.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		16052/16053-17057/17058 (1005 bp deletion)
Chromosome		II
Putative gene structure		join(15579..15650, 15790..15900, 15949..16196, 16249..17099, 17249..17331)
Map position		-0.52
Balancer
Map position of balancer
Sequence of primers		IntFwd:ACTTCAGAATGCCTCTGCGA,ExtRev:CCTTTTGCAGATGCCACCCA,IntRev:CCCATGCTGGATTCAGAAGA,ExtFwd:TGCCATCTTGACTTGCAGGT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Abay-Nørgaard S, Attianese B, Boreggio L, Salcini AE. Regulators of H3K4 methylation mutated in neurodevelopmental disorders control axon guidance in Caenorhabditis elegans. Development 2020 147(15)   [ PubMed ID = 32675280 ] [ RRC reference ] Li T, Kelly WG. A role for Set1/MLL-related components in epigenetic regulation of the Caenorhabditis elegans germ line. PLoS Genet 2011 7(3) e1001349  [ PubMed ID = 21455483 ] [ RRC reference ] Wang S, Fisher K, Poulin GB. Lineage specific trimethylation of H3 on lysine 4 during C. elegans early embryogenesis. Dev Biol 2011 355(2) 227-38  [ PubMed ID = 21549110 ] [ RRC reference ] Poole RJ, Bashllari E, Cochella L, Flowers EB, Hobert O. A Genome-Wide RNAi Screen for Factors Involved in Neuronal Specification in Caenorhabditis elegans. PLoS Genet 2011 7(6) e1002109  [ PubMed ID = 21698137 ] [ RRC reference ] Avgousti DC, Cecere G, Grishok A. The conserved PHD1-PHD2 domain of ZFP-1/AF10 is a discrete functional module essential for viability in Caenorhabditis elegans. Mol Cell Biol 2013 33(5) 999-1015  [ PubMed ID = 23263989 ] [ RRC reference ] Li T, Kelly WG. A role for WDR5 in TRA-1/Gli mediated transcriptional control of the sperm/oocyte switch in C. elegans. Nucleic Acids Res 2014 42(9) 5567-81  [ PubMed ID = 24682813 ] [ RRC reference ]