分離済み変異体

tm3433

Allele Nametm3433
Allele Type通常株
Sequence NameC27A7.4
Gene Nameche-11
Worm BaseAllele Name tm3433
Gene Name che-11
Sequence C27A7.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 19399/19400-19939/19940 (540 bp deletion)
ChromosomeV
Putative gene structurecomplement(join(17635..17972, 18027..18189, 18234..18446, 18489..18610, 18658..19472, 19520..19900, 19948..20056, 20103..20316, 20425..20706, 20752..20869, 20919..21184, 21231..21496, 22134..22455, 23059..23251, 23301..23422, 23470..23555, 23607..23679))
Map position3.67
Balancer
Map position of balancer
Sequence of primersExtFwd:CCAGGAAGATCTTCGTAGTA,IntFwd:CCACCCGCCATCAAGCATAA,ExtRev:GGTAGTCACTTATGACGTAC,IntRev:TGGATGGCAGTTGCTACTAC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Park K, Li C, Tsiropoulou S, Gonçalves J, Kondratev C, Pelletier L, Blacque OE, Leroux MR.
CDKL kinase regulates the length of the ciliary proximal segment.
Curr Biol 2021 31(11) 2359-2373.e7 
[ PubMed ID = 33857430 ] [ RRC reference ]

Cevik S, Kaplan OI.
Subcellular localization of the voltage-gated K+ channel EGL-36 , a member of the KV3 subfamily, in the ciliated sensory neurons in C. elegans.
MicroPubl Biol 2021 2021  
[ PubMed ID = 33688626 ] [ RRC reference ]

Serwas D, Su TY, Roessler M, Wang S, Dammermann A.
Centrioles initiate cilia assembly but are dispensable for maturation and maintenance in C. elegans.
J Cell Biol 2017 216(6) 1659-1671 
[ PubMed ID = 28411189 ] [ RRC reference ]

Prevo B, Mangeol P, Oswald F, Scholey JM, Peterman EJ.
Functional differentiation of cooperating kinesin-2 motors orchestrates cargo import and transport in C. elegans cilia.
Nat Cell Biol 2015 17(12) 1536-45 
[ PubMed ID = 26523365 ] [ RRC reference ]