分離済み変異体

tm3419

Allele Nametm3419
BalanceCompleted
OutCrossNot Accepted
Sequence NameY39G10AR.5
Gene NameY39G10AR.5
Worm BaseAllele Name tm3419 (x1)
Gene Name Y39G10AR.5
Sequence Y39G10AR.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 60599/60600-60820/60821 (221 bp deletion)
ChromosomeI
Putative gene structurejoin(60057..60123, 60599..60679, 60792..60977, 62372..62533, 63370..63495, 63540..63656, 64640..64741, 64821..64988, 65036..65163, 65750..66015, 66063..66217, 66264..66576, 67321..67923, 68338..68740)
Map position-9.13
BalancerhT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersIntFwd:CAAGCGTCCCCATAAATATG,ExtFwd:CCCGTGATACTACAGGTGTG,IntRev:CGAGCGCTATAACAAGATAC,ExtRev:AACGCAACTAGACCAATGAC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Caro L, Wei AD, Thomas CA, Posch G, Uremis A, Franzi MC, Abell SJ, Laszlo AH, Gundlach JH, Ramirez JM, Ailion M.
An animal toxin-antidote system kills cells by creating a novel cation channel.
PLoS Biol 2025 23(5) e3003182 
[ PubMed ID = 40424258 ] [ RRC reference ]

Caro L, Wei AD, Thomas CA, Posch G, Uremis A, Franzi MC, Abell SJ, Laszlo AH, Gundlach JH, Ramirez JM, Ailion M.
Mechanism of an animal toxin-antidote system.
bioRxiv 2024   
[ PubMed ID = 38915716 ] [ RRC reference ]

Seidel HS, Ailion M, Li J, van Oudenaarden A, Rockman MV, Kruglyak L.
A novel sperm-delivered toxin causes late-stage embryo lethality and transmission ratio distortion in C. elegans.
PLoS Biol 2011 9(7) e1001115 
[ PubMed ID = 21814493 ] [ RRC reference ]