分離済み変異体

tm3411

Allele Name

tm3411

Balance

Completed

OutCross

Not Accepted

Sequence Name

T19E7.2

Gene Name

skn-1

Worm Base

Allele Name

tm3411 (x1)

Gene Name

skn-1

Sequence

T19E7.2

Phenotype

lethal or sterile.

Mutation site

274/275-586/587 (312 bp deletion)

Chromosome

Putative gene structure

complement(join(36..112, 165..532, 686..944, 1621..1773, 1827..2148, 3455..3877)), complement(join(36..112, 165..532, 686..944, 1139..1367))

Map position

2.02

Balancer

nT1 [qIs51]

Map position of balancer

Sequence of primers

ExtFwd:AGGGCTTCTCAGATGTAATG,IntFwd:GGGACATCTTGTCGTGACGA,ExtRev:CATATCTTGGAATGGCAGAG,IntRev:GTTAACCTAGAAGCGGCTTA

Distributed lab

Depositor

Dr. S. Mitani

References

Please submit your publication

Cornwell AB, Zhang Y, Thondamal M, Johnson DW, Thakar J, Samuelson AV.
The C. elegans Myc-family of transcription factors coordinate a dynamic adaptive response to dietary restriction.
Geroscience 2024 46(5) 4827-4854
[ PubMed ID = 38878153 ] [ RRC reference ]

Cornwell A, Zhang Y, Thondamal M, Johnson DW, Thakar J, Samuelson AV.
The C. elegans Myc-family of transcription factors coordinate a dynamic adaptive response to dietary restriction.
bioRxiv 2023
[ PubMed ID = 38045350 ] [ RRC reference ]

Yang R, Kang Y, Duan J, Zou C, Wu Q.
The p38 MAPK/PMK-1 Pathway Is Required for Resistance to Nocardia farcinica Infection in Caenorhabditis elegance.
Pathogens 2022 11(10)
[ PubMed ID = 36297128 ] [ RRC reference ]

Joshi KK, Matlack TL, Rongo C.
Dopamine signaling promotes the xenobiotic stress response and protein homeostasis.
EMBO J 2016 35(17) 1885-901
[ PubMed ID = 27261197 ] [ RRC reference ]

Dresen A, Finkbeiner S, Dottermusch M, Beume JS, Li Y, Walz G, Neumann-Haefelin E.
Caenorhabditis elegans OSM-11 signaling regulates SKN-1/Nrf during embryonic development and adult longevity and stress response.
Dev Biol 2015 400(1) 118-31
[ PubMed ID = 25637691 ] [ RRC reference ]

Ewald CY, Landis JN, Porter Abate J, Murphy CT, Blackwell TK.
Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity.
Nature 2015 519(7541) 97-101
[ PubMed ID = 25517099 ] [ RRC reference ]

Ruf V, Holzem C, Peyman T, Walz G, Blackwell TK, Neumann-Haefelin E.
TORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development.
Dev Biol 2013 384(2) 214-27
[ PubMed ID = 23973804 ] [ RRC reference ]

Ghose P, Park EC, Tabakin A, Salazar-Vasquez N, Rongo C.
Anoxia-reoxygenation regulates mitochondrial dynamics through the hypoxia response pathway, SKN-1/Nrf, and stomatin-like protein STL-1/SLP-2.
PLoS Genet 2013 9(12) e1004063
[ PubMed ID = 24385935 ] [ RRC reference ]