分離済み変異体

tm3395

Allele Nametm3395
BalanceCompleted
OutCrossNot Accepted
Sequence NameC18E3.2
Gene NameC18E3.2
Worm BaseAllele Name tm3395 (x1)
Gene Name C18E3.2
Sequence C18E3.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 26234/26235-TT-26655/26656 (421 bp deletion + 2 bp insertion)
ChromosomeI
Putative gene structurejoin(25966..26016, 26085..26228, 26276..27360, 27412..27481)
Map position-1.59
Balancer,hT2
Map position of balancer
Sequence of primersIntRev:CCCCATCCCTGAGCATTTAA,IntFwd:ATGGGCCTCGAATGGTTGCA,ExtRev:AATCTCAACCCCCATCCCTG,ExtFwd:CGGGAGGTTTTGCTGGTCAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Bowman R, Balukoff N, Clemons A, Koury E, Ford T, Baxi K, Egydio de Carvalho C, Smolikove S.
Akirin Is Required for Muscle Function and Acts Through the TGF-β Sma/Mab Signaling Pathway in Caenorhabditis elegans Development.
G3 (Bethesda) 2020 10(1) 387-400 
[ PubMed ID = 31767636 ] [ RRC reference ]

Ertl I, Porta-de-la-Riva M, Gómez-Orte E, Rubio-Peña K, Aristizábal-Corrales D, Cornes E, Fontrodona L, Osteikoetxea X, Ayuso C, Askjaer P, Cabello J, Cerón J.
Functional Interplay of Two Paralogs Encoding SWI/SNF Chromatin-Remodeling Accessory Subunits During Caenorhabditis elegans Development.
Genetics 2016 202(3) 961-75 
[ PubMed ID = 26739451 ] [ RRC reference ]

Mathies LD, Blackwell GG, Austin MK, Edwards AC, Riley BP, Davies AG, Bettinger JC.
SWI/SNF chromatin remodeling regulates alcohol response behaviors in Caenorhabditis elegans and is associated with alcohol dependence in humans.
Proc Natl Acad Sci U S A 2015 112(10) 3032-7 
[ PubMed ID = 25713357 ] [ RRC reference ]

Large EE, Mathies LD.
Caenorhabditis elegans SWI/SNF subunits control sequential developmental stages in the somatic gonad.
G3 (Bethesda) 2014 4(3) 471-83 
[ PubMed ID = 24402584 ] [ RRC reference ]