Home > 分離済み変異体 > tm3378

分離済み変異体

Allele Name		tm3378
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F02H6.5
Gene Name		F02H6.5
Worm Base	Allele Name	tm3378
	Gene Name	F02H6.5
	Sequence	F02H6.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		24349/24350-24794/24795 (445 bp deletion)
Chromosome		IV
Putative gene structure		join(23025..23049, 23971..24308, 24582..24680, 25326..25619, 25786..25956, 26121..26228, 26539..26682, 27113..27349)
Map position		11.6
Balancer
Map position of balancer
Sequence of primers		IntRev:CCGCGGATTTCTAGATATAG,ExtRev:ACAGTGCATTTCCACCCTGA,IntFwd:CCATGATGGAAGCCCGGAAT,ExtFwd:CGGAGAGAGCGATAGAATCT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Pu L, Zhao L, Wang J, Deleuze C, Nilsson L, Henriksson J, Laurent P, Chen C. Avoidance of hydrogen sulfide is modulated by external and internal states in Caenorhabditis elegans. Elife 2025 12   [ PubMed ID = 41288154 ] [ RRC reference ] Guzman G, Jahn H, Farley SE, Kyle JE, Bramer LM, Hoetzl S, van den Dikkenberg J, Hermansson M, Holthuis JCM, Tafesse FG. Characterization of Caenorhabditis elegans sphingomyelin synthases through heterologous expression. J Biol Chem 2025 301(7) 110300  [ PubMed ID = 40473211 ] [ RRC reference ] Romanelli-Cedrez L, Vairoletti F, Salinas G. Rhodoquinone-dependent electron transport chain is essential for Caenorhabditis elegans survival in hydrogen sulfide environments. J Biol Chem 2024 300(9) 107708  [ PubMed ID = 39178951 ] [ RRC reference ] Feng D, Qu L, Powell-Coffman JA. Whole genome profiling of short-term hypoxia induced genes and identification of HIF-1 binding sites provide insights into HIF-1 function in Caenorhabditis elegans. PLoS One 2024 19(5) e0295094  [ PubMed ID = 38743782 ] [ RRC reference ] Romanelli-Credrez L, Doitsidou M, Alkema MJ, Salinas G. HIF-1 Has a Central Role in Caenorhabditis elegans Organismal Response to Selenium. Front Genet 2020 11 63  [ PubMed ID = 32161616 ] [ RRC reference ] Horsman JW, Heinis FI, Miller DL. A Novel Mechanism To Prevent H2S Toxicity in Caenorhabditis elegans. Genetics 2019 213(2) 481-490  [ PubMed ID = 31371406 ] [ RRC reference ] Horsman JW, Miller DL. Mitochondrial Sulfide Quinone Oxidoreductase Prevents Activation of the Unfolded Protein Response in Hydrogen Sulfide. J Biol Chem 2016 291(10) 5320-5  [ PubMed ID = 26677221 ] [ RRC reference ] Budde MW, Roth MB. The response of Caenorhabditis elegans to hydrogen sulfide and hydrogen cyanide. Genetics 2011 189(2) 521-32  [ PubMed ID = 21840852 ] [ RRC reference ]