分離済み変異体

tm3334

Allele Nametm3334
Allele Type通常株
Sequence NameF09E10.8
Gene Nametoca-1
Worm BaseAllele Name tm3334
Gene Name toca-1
Sequence F09E10.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. K. Oegema: wt dyf.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 27325/27326-28479/28480 (1154 bp deletion)
ChromosomeX
Putative gene structurecomplement(join(24644..24713, 24843..25000, 25737..26353, 27287..27597, 28200..28484, 29314..29429, 34938..34970))
Map position-17.93
Balancer
Map position of balancer
Sequence of primersExtFwd:AGTGGGATCCTTCCCCTGTG,IntFwd:TGTGCCGGGATTCCCTGATC,ExtRev:ACAGGAATGTACCTACCTAG,IntRev:GTACCTACCTAGGAATCCTG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Yang Q, Roiz D, Mereu L, Daube M, Hajnal A.
The Invading Anchor Cell Induces Lateral Membrane Constriction during Vulval Lumen Morphogenesis in C. elegans.
Dev Cell 2017 42(3) 271-285.e3 
[ PubMed ID = 28787593 ] [ RRC reference ]

Alan JK, Struckhoff EC, Lundquist EA.
Multiple cytoskeletal pathways and PI3K signaling mediate CDC-42-induced neuronal protrusion in C. elegans.
Small GTPases 2013 4(4) 208-20 
[ PubMed ID = 24149939 ] [ RRC reference ]

Giuliani C, Troglio F, Bai Z, Patel FB, Zucconi A, Malabarba MG, Disanza A, Stradal TB, Cassata G, Confalonieri S, Hardin JD, Soto MC, Grant BD, Scita G.
Requirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesis.
PLoS Genet 2009 5(10) e1000675 
[ PubMed ID = 19798448 ] [ RRC reference ]