分離済み変異体

tm3278

Allele Nametm3278
BalanceNot Required
OutCrossNot Accepted
Sequence NameF28D1.9
Gene Nameacs-20
Worm BaseAllele Name tm3278
Gene Name acs-20
Sequence F28D1.9
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. S. Mitani: PLoS One, 5 (1), e8857 (2010).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 23878/23879-24544/24545 (666 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(22436..22590, 23485..24099, 24291..24407, 24464..24808, 24857..25018, 25069..25267, 25537..25636, 25681..25776, 26557..26720))
Map position5.91
Balancer
Map position of balancer
Sequence of primersExtFwd:ATCGCGTAGCTGGTAAGCGA,IntFwd:ACTCGAACAACTGACGCCAT,ExtRev:TTGAGGTTTACTCTGTCGGA,IntRev:ACTACGGAACCAAAGACCCT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Labarre A, Guitard E, Tossing G, Forest A, Bareke E, Labrecque M, Tétreault M, Ruiz M, Alex Parker J.
Fatty acids derived from the probiotic Lacticaseibacillus rhamnosus HA-114 suppress age-dependent neurodegeneration.
Commun Biol 2022 5(1) 1340 
[ PubMed ID = 36477191 ] [ RRC reference ]

Ward JD, Mullaney B, Schiller BJ, He LD, Petnic SE, Couillault C, Pujol N, Bernal TU, Van Gilst MR, Ashrafi K, Ewbank JJ, Yamamoto KR.
Defects in the C. elegans acyl-CoA synthase, acs-3, and nuclear hormone receptor, nhr-25, cause sensitivity to distinct, but overlapping stresses.
PLoS One 2014 9(3) e92552 
[ PubMed ID = 24651852 ] [ RRC reference ]

Kage-Nakadai E, Kobuna H, Kimura M, Gengyo-Ando K, Inoue T, Arai H, Mitani S.
Two very long chain fatty acid acyl-CoA synthetase genes, acs-20 and acs-22, have roles in the cuticle surface barrier in Caenorhabditis elegans.
PLoS One 2010 5(1) e8857 
[ PubMed ID = 20111596 ] [ RRC reference ]