分離済み変異体

tm3268

Allele Name

tm3268

Balance

Not Required

OutCross

Not Accepted

Sequence Name

F58G6.4

Gene Name

acc-1

Worm Base

Allele Name

tm3268

Gene Name

acc-1

Sequence

F58G6.4

Phenotype

homozygous viable. Dr. H. Sawa: not Psa. Dr. C. Bargmann: reduced locomotion on food.

Mutation site

22068/22069-TCGA-22309/22310 (241 bp deletion + 4 bp insertion)

Chromosome

Putative gene structure

join(21216..21356, 21403..21496, 21644..21809, 21970..22101, 22250..22373, 22457..22536, 22588..22647, 22789..22996, 23190..23276, 23325..23390, 23659..23789, 23944..23985, 24036..24105)

Map position

4.35

Balancer

Map position of balancer

Sequence of primers

IntRev:CAACTCACTTTAGGCGGTAG,IntFwd:CCGGGTTGGATTATGGTGTC,ExtRev:GTGCGGACTAGTTTGCATAC,ExtFwd:TTAGATGAGTCATCCGGGTT

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Zou W, Fan Y, Liu J, Cheng H, Hong H, Al-Sheikh U, Li S, Zhu L, Li R, He L, Tang YQ, Zhao G, Zhang Y, Wang F, Zhan R, Zheng X, Kang L.
Anoctamin-1 is a core component of a mechanosensory anion channel complex in C. elegans.
Nat Commun 2025 16(1) 1680
[ PubMed ID = 39956854 ] [ RRC reference ]

Huo J, Xu T, Liu Q, Polat M, Kumar S, Zhang X, Leifer AM, Wen Q.
Hierarchical behavior control by a single class of interneurons.
Proc Natl Acad Sci U S A 2024 121(47) e2410789121
[ PubMed ID = 39531495 ] [ RRC reference ]

Kumar S, Sharma AK, Leifer AM.
An inhibitory acetylcholine receptor gates context-dependent mechanosensory processing in C. elegans.
iScience 2024 27(10) 110776
[ PubMed ID = 39381742 ] [ RRC reference ]

Kumar S, Sharma AK, Leifer AM.
An inhibitory acetylcholine receptor gates context dependent mechanosensory processing in C. elegans.
bioRxiv 2024
[ PubMed ID = 38585821 ] [ RRC reference ]

Zhan X, Chen C, Niu L, Du X, Lei Y, Dan R, Wang ZW, Liu P.
Locomotion modulates olfactory learning through proprioception in C. elegans.
Nat Commun 2023 14(1) 4534
[ PubMed ID = 37500635 ] [ RRC reference ]

Hori S, Mitani S.
The transcription factor unc-130/FOXD3/4 contributes to the biphasic calcium response required to optimize avoidance behavior.
Sci Rep 2022 12(1) 1907
[ PubMed ID = 35115609 ] [ RRC reference ]

Takayanagi-Kiya S, Zhou K, Jin Y.
Release-dependent feedback inhibition by a presynaptically localized ligand-gated anion channel.
Elife 2016 5
[ PubMed ID = 27782882 ] [ RRC reference ]

Li Z, Liu J, Zheng M, Xu XZ.
Encoding of both analog- and digital-like behavioral outputs by one C. elegans interneuron.
Cell 2014 159(4) 751-65
[ PubMed ID = 25417153 ] [ RRC reference ]