分離済み変異体

tm3256

Allele Nametm3256
Allele Type通常株
Sequence NameH25K10.5
Gene NameH25K10.5
Worm BaseAllele Name tm3256
Gene Name H25K10.5
Sequence H25K10.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 29052/29053-29662/29663 (610 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(27130..27215, 27274..27403, 27449..27516, 27569..27947, 28769..29052, 29101..29295, 29353..29601, 29647..29806))
Map position14.62
Balancer
Map position of balancer
Sequence of primersIntRev:CCATGAGCAATATTACCCGA,IntFwd:CGGTTATCTAGGTGTGGCCT,ExtRev:CTACATCCAGTGATGGTCTT,ExtFwd:CCTAACGCATACTACCGGTT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Yu S, Driscoll M.
EGF signaling comes of age: promotion of healthy aging in C. elegans.
Exp Gerontol 2011 46(2-3) 129-34 
[ PubMed ID = 21074601 ] [ RRC reference ]

Detienne G, De Haes W, Ernst UR, Schoofs L, Temmerman L.
Royalactin extends lifespan of Caenorhabditis elegans through epidermal growth factor signaling.
Exp Gerontol 2014 60 129-35 
[ PubMed ID = 25456847 ] [ RRC reference ]

Iwasa H, Yu S, Xue J, Driscoll M.
Novel EGF pathway regulators modulate C. elegans healthspan and lifespan via EGF receptor, PLC-gamma, and IP3R activation.
Aging Cell 2010 9(4) 490-505 
[ PubMed ID = 20497132 ] [ RRC reference ]