分離済み変異体

tm3236

Allele Name

tm3236

Balance

Not Required

OutCross

Not Accepted

Sequence Name

D1009.1a

Gene Name

acs-22

Worm Base

Allele Name

tm3236

Gene Name

acs-22

Sequence

D1009.1a

Phenotype

homozygous viable. Dr. S. Mitani: PLoS One, 5 (1), e8857 (2010).

Mutation site

36159/36160-36574/36575 (415 bp deletion)

Chromosome

Putative gene structure

join(30386..30390, 33624..33797, 34402..34489, 34620..34727, 35690..35888, 35971..36427, 36472..36635, 37023..37468, 37555..37620, 37675..37771, 37822..37985)

Map position

0.45

Balancer

Map position of balancer

Sequence of primers

ExtFwd:CTTGGGTTCACATCGTACGT,IntFwd:GGTTACAAAATGGGCGACGT,ExtRev:AGCAGTCCTGGAAATACGTC,IntRev:GAGCCGTACAACTCTCCAAT

Distributed lab

Depositor

Dr. S. Mitani

References

Please submit your publication

Ruan M, Xu F, Li N, Yu J, Teng F, Tang J, Huang C, Zhu H.
Free long-chain fatty acids trigger early postembryonic development in starved Caenorhabditis elegans by suppressing mTORC1.
PLoS Biol 2024 22(10) e3002841
[ PubMed ID = 39436954 ] [ RRC reference ]

Mørch MGM, Møller KV, Hesselager MO, Harders RH, Kidmose CL, Buhl T, Fuursted K, Bendixen E, Shen C, Christensen LG, Poulsen CH, Olsen A.
The TGF-β ligand DBL-1 is a key player in a multifaceted probiotic protection against MRSA in C. elegans.
Sci Rep 2021 11(1) 10717
[ PubMed ID = 34021197 ] [ RRC reference ]

Li S, Li Q, Kong Y, Wu S, Cui Q, Zhang M, Zhang SO.
Specific regulation of thermosensitive lipid droplet fusion by a nuclear hormone receptor pathway.
Proc Natl Acad Sci U S A 2017 114(33) 8841-8846
[ PubMed ID = 28760992 ] [ RRC reference ]

Li S, Xu S, Ma Y, Wu S, Feng Y, Cui Q, Chen L, Zhou S, Kong Y, Zhang X, Yu J, Wu M, Zhang SO.
A Genetic Screen for Mutants with Supersized Lipid Droplets in Caenorhabditis elegans.
G3 (Bethesda) 2016 6(8) 2407-19
[ PubMed ID = 27261001 ] [ RRC reference ]

Imae R, Inoue T, Kimura M, Kanamori T, Tomioka NH, Kage-Nakadai E, Mitani S, Arai H.
Intracellular phospholipase A1 and acyltransferase, which are involved in Caenorhabditis elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol.
Mol Biol Cell 2010 21(18) 3114-24
[ PubMed ID = 20668164 ] [ RRC reference ]

Kage-Nakadai E, Kobuna H, Kimura M, Gengyo-Ando K, Inoue T, Arai H, Mitani S.
Two very long chain fatty acid acyl-CoA synthetase genes, acs-20 and acs-22, have roles in the cuticle surface barrier in Caenorhabditis elegans.
PLoS One 2010 5(1) e8857
[ PubMed ID = 20111596 ] [ RRC reference ]