分離済み変異体

tm3200

Allele Nametm3200
BalanceCompleted
OutCrossNot Accepted
Sequence NameC27F2.5
Gene NameC27F2.5
Worm BaseAllele Name tm3200 (x1)
Gene Name C27F2.5
Sequence C27F2.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. M. Han: early larval lethal.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 3381/3382-TAAACCGAAACCAAG-3848/3849 (467 bp deletion + 15 bp insertion)
ChromosomeIII
Putative gene structurecomplement(join(3229..3421, 3485..3673, 3716..3822, 3873..3946, 3995..4101, 4150..4226, 4269..4331))
Map position-2.31
BalancerhT2,hT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersIntRev:TTCCCAGGATGGCGACACGA,ExtFwd:TGAAGGGAACCAGTATTGTG,IntFwd:GTTGTATCGGATGCCTGTTC,ExtRev:GGTGGCATGCCACTTTAAAC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Lefebvre C, Largeau C, Michelet X, Fourrage C, Maniere X, Matic I, Legouis R, Culetto E.
The ESCRT-II proteins are involved in shaping the sarcoplasmic reticulum in C. elegans.
J Cell Sci 2016 129(7) 1490-9 
[ PubMed ID = 26906413 ] [ RRC reference ]

Djeddi A, Michelet X, Culetto E, Alberti A, Barois N, Legouis R.
Induction of autophagy in ESCRT mutants is an adaptive response for cell survival in C. elegans.
J Cell Sci 2012 125(Pt 3) 685-94 
[ PubMed ID = 22389403 ] [ RRC reference ]