分離済み変異体

tm3197

Allele Nametm3197
BalanceNot Required
OutCrossNot Accepted
Sequence NameC29F7.6
Gene Namejmjd-3.3
Worm BaseAllele Name tm3197
Gene Name jmjd-3.3
Sequence C29F7.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. R.H. Horvitz: pharyngeal morphology normal. Dr. Hongkyun Kim: normal locomotion. Dr. M. Han: normal vulval phenotype.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 30405/30406-30657/30658 (252 bp deletion)
ChromosomeX
Putative gene structurejoin(28617..28785, 28994..29226, 30312..31107, 31484..31686, 32136..32719, 32961..33170, 33217..33572)
Map position12.4
Balancer
Map position of balancer
Sequence of primersExtFwd:CTAATCGTCCTGACTACATG,IntFwd:CTTACTTCTGGAGTACGGCA,ExtRev:GAGACTTTGACGCACGTATG,IntRev:CCAAACTACCCTTACTCGTG
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Zaghet N, Madsen K, Rossi F, Perez DF, Amendola PG, Demharter S, Pfisterer U, Khodosevich K, Pasini D, Salcini AE.
Coordinated maintenance of H3K36/K27 methylation by histone demethylases preserves germ cell identity and immortality.
Cell Rep 2021 37(8) 110050 
[ PubMed ID = 34818537 ] [ RRC reference ]

Guillermo ARR, Chocian K, Gavriilidis G, Vandamme J, Salcini AE, Mellor J, Woollard A.
H3K27 modifiers regulate lifespan in C. elegans in a context-dependent manner.
BMC Biol 2021 19(1) 59 
[ PubMed ID = 33766022 ] [ RRC reference ]

McDiarmid TA, Belmadani M, Liang J, Meili F, Mathews EA, Mullen GP, Hendi A, Wong WR, Rand JB, Mizumoto K, Haas K, Pavlidis P, Rankin CH.
Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation.
Proc Natl Acad Sci U S A 2020 117(1) 656-667 
[ PubMed ID = 31754030 ] [ RRC reference ]

Greer EL, Beese-Sims SE, Brookes E, Spadafora R, Zhu Y, Rothbart SB, Aristizábal-Corrales D, Chen S, Badeaux AI, Jin Q, Wang W, Strahl BD, Colaiácovo MP, Shi Y.
A histone methylation network regulates transgenerational epigenetic memory in C. elegans.
Cell Rep 2014 7(1) 113-26 
[ PubMed ID = 24685137 ] [ RRC reference ]