Home > 分離済み変異体 > tm3188

分離済み変異体

Allele Name		tm3188
Allele Type		通常株
Sequence Name		K08E7.1
Gene Name		eak-7
Worm Base	Allele Name	tm3188
	Gene Name	eak-7
	Sequence	K08E7.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		4705/4706-5222/5223 (517 bp deletion)
Chromosome		IV
Putative gene structure		complement(join(3087..3284, 3345..3467, 3549..3694, 4139..4565, 4613..4792, 4848..4973))
Map position		6.02
Balancer
Map position of balancer
Sequence of primers		IntFwd:TGTGTACCTTGCGAGGCGAA,ExtRev:GCACGTGTTGAGAGGATTCA,IntRev:ACTATGTTGTGCCTCCTGCT,ExtFwd:TAACACAGCCATGTGTGGAT
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Itani OA, Flibotte S, Dumas KJ, Moerman DG, Hu PJ. Chromoanasynthetic Genomic Rearrangement Identified in a N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Screen in Caenorhabditis elegans. G3 (Bethesda) 2015 6(2) 351-6  [ PubMed ID = 26628482 ] [ RRC reference ] Itani OA, Flibotte S, Dumas KJ, Guo C, Blumenthal T, Hu PJ. N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Reveals an Intronic Residue Critical for Caenorhabditis elegans 3' Splice Site Function in Vivo. G3 (Bethesda) 2016 6(6) 1751-6  [ PubMed ID = 27172199 ] [ RRC reference ] Delaney CE, Chen AT, Graniel JV, Dumas KJ, Hu PJ. A histone H4 lysine 20 methyltransferase couples environmental cues to sensory neuron control of developmental plasticity. Development 2017 144(7) 1273-1282  [ PubMed ID = 28209779 ] [ RRC reference ] Ferguson AA, Roy S, Kormanik KN, Kim Y, Dumas KJ, Ritov VB, Matern D, Hu PJ, Fisher AL. TATN-1 mutations reveal a novel role for tyrosine as a metabolic signal that influences developmental decisions and longevity in Caenorhabditis elegans. PLoS Genet 2013 9(12) e1004020  [ PubMed ID = 24385923 ] [ RRC reference ] Dumas KJ, Delaney CE, Flibotte S, Moerman DG, Csankovszki G, Hu PJ. Unexpected role for dosage compensation in the control of dauer arrest, insulin-like signaling, and FoxO transcription factor activity in Caenorhabditis elegans. Genetics 2013 194(3) 619-29  [ PubMed ID = 23733789 ] [ RRC reference ] Alam H, Williams TW, Dumas KJ, Guo C, Yoshina S, Mitani S, Hu PJ. EAK-7 controls development and life span by regulating nuclear DAF-16/FoxO activity. Cell Metab 2010 12(1) 30-41  [ PubMed ID = 20620993 ] [ RRC reference ]