分離済み変異体

tm3172

Allele Nametm3172
BalanceNot Required
OutCrossNot Accepted
Sequence NameC06A8.9
Gene Nameglr-4
Worm BaseAllele Name tm3172 (x1)
Gene Name glr-4
Sequence C06A8.9
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 24559/24560-AAAAAAAAAATACTG-25133/25134 (574 bp deletion + 15 bp insertion)
ChromosomeII
Putative gene structurecomplement(join(22226..22469, 23562..23656, 23703..23818, 23865..23930, 24050..24173, 24221..24392, 24452..24560, 24608..24858, 24905..25094, 25145..25250, 25297..25557, 28913..29020, 29813..29902, 29994..30059, 30105..30206, 30251..30352, 30404..30718, 30767..30867, 30979..31122, 31167..31260))
Map position0.57
Balancer,mIn1 [e128 mIs14]
Map position of balancer
Sequence of primersExtFwd:GTTACCTCGATACCAGTCCA,IntRev:CAGAGGACTTGGAGGGATTA,IntFwd:CGATACCAGTCCATGAACTG,ExtRev:CGTGGCTGGAACTTTGACAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Liu Y, Huang L, Wang R, Qi F, Liu Y, Chen Q, Mialon M, Chen L, Pinan-Lucarre B, Gao S.
Nicotine induces abnormal motor coupling through sensitization of a mechanosensory circuit in Caenorhabditis elegans.
PLoS Biol 2025 23(10) e3003423 
[ PubMed ID = 41042799 ] [ RRC reference ]

Zhang Y, Shi Y, Zeng K, Chen L, Gao S.
Hierarchical competing inhibition circuits govern motor stability in C. elegans.
Nat Commun 2025 16(1) 4405 
[ PubMed ID = 40355468 ] [ RRC reference ]