分離済み変異体

tm3165

Allele Nametm3165
BalanceNot Required
OutCrossNot Accepted
Sequence NameH17B01.1
Gene Namefgt-1
Worm BaseAllele Name tm3165
Gene Name fgt-1
Sequence H17B01.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 35925/35926-36276/36277 (351 bp deletion)
ChromosomeII
Putative gene structurejoin(34864..34926, 35222..35320, 36002..36081, 36178..36383, 36846..37080, 37365..37521, 38648..38956, 39035..39226, 39846..39983)
Map position-15.37
Balancer
Map position of balancer
Sequence of primersIntFwd:GCGGGGGTTCAGCTGTGTAA,ExtFwd:CCGCAACCCTTTCATTATAC,ExtRev:AAGGGCTGAGGAGAATCCTG,IntRev:TATGATACGGAGTTTCGCCA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Lionaki E, Gkikas I, Daskalaki I, Ioannidi MK, Klapa MI, Tavernarakis N.
Mitochondrial protein import determines lifespan through metabolic reprogramming and de novo serine biosynthesis.
Nat Commun 2022 13(1) 651 
[ PubMed ID = 35115503 ] [ RRC reference ]

Kitaoka S, Morielli AD, Zhao FQ.
FGT-1-mediated glucose uptake is defective in insulin/IGF-like signaling mutants in Caenorhabditis elegans.
FEBS Open Bio 2016 6(6) 576-85 
[ PubMed ID = 27419060 ] [ RRC reference ]

Kitaoka S, Morielli AD, Zhao FQ.
FGT-1 is a mammalian GLUT2-like facilitative glucose transporter in Caenorhabditis elegans whose malfunction induces fat accumulation in intestinal cells.
PLoS One 2013 8(6) e68475 
[ PubMed ID = 23826391 ] [ RRC reference ]